Protein Alignment Kul and LOC100491788

DIOPT Version :10

• Sequence 1: NP_651716.1
• Gene: Kul / 43501
• FlyBaseID: FBgn0039688
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_001265673.1
• Gene: LOC100491788 / 100491788
• XenbaseID: XB-GENE-29080867
• Length: 725
• Species: Xenopus tropicalis
• Alignment Length: 989
• Identity: 254/989 - (25%)
• Similarity: 378/989 - (38%)
• Gaps: 332/989 - (33%)

  Fly    43 YIKHWEAANFDRQVLQAAQVRHLEQARFRQKR----EVTPSASGLAHTIRLNFSAHDRDFRLVLR 103
            ::|::|..:||.        ..|:|...|.||    |..|        |.|:|.|:.|.|.|:||
 Frog    34 FLKYYENLSFDN--------HDLDQKHKRSKRASEEEKEP--------IYLDFFAYKRKFALILR 82

  Fly   104 QQPHSVFAHDVEIENTLGPIDYDVSRIYTGSLEDDEAAHVQAILTSDNLLDGTIETQAEHYYIEP 168
            :. .:|||.|.::.:....:..|:|.:|:|:|:|:..:.....:. |...:|.|:|:...:|:|
 Frog    83 RD-LNVFADDFQVVSNNRTLSVDISFVYSGALKDEFGSFCHGSII-DGHFEGFIQTKNGTFYVE- 144

  Fly   169 AHRYSQQLAESGVHSIVYKLSDVNMQKQQFTGGGLNSATPAKTHCASEKLRKKRWLPEELAMSDA 233
                                                                             
 Frog   145 ----------------------------------------------------------------- 144

  Fly   234 PAPTYNRNPPLPLDLEVPYNDDFRVLASEEDKSEESPRKYPTTSTTRSTVRSTESFLATLTKPTS 298
                |.:|                     .:.:||| ..|.......|.::..:||..||.|
 Frog   145 ----YEKN---------------------SNGTEES-YIYHEEDIGYSILKDIKSFELTLKK--- 180

  Fly   299 NRNILVNNYNPSNLGEGSRSYSSGNNNANSNSNNNNSNNNNNNNNSNNNVRKLYTKHKNIIVSTY 363
                                |..                          :.|:..|.|.
 Frog   181 --------------------YQF--------------------------LEKMKWKAKE------ 193

  Fly   364 NRPIEPEFGTPYEEPNNNGTRELPSNFFNANWTTLFLGNNNNGNDRPSHKTHVEIITKNGATKKP 428
                                                                             
 Frog   194 ----------------------------------------------------------------- 193

  Fly   429 NIIVNNYNPEIIFAPNPHNPSFNSMMMTNLLSGRGGEDIHSSPRLLYDRKTTCMLYLQADHTFFQ 493
                                                ||:....|.|...:|||:|||:||:.|::
 Frog   194 ------------------------------------EDLTRKKRSLDLSRTTCLLYLKADYLFYK 222

  Fly   494 KMGSDEASIEAITRHVQRANTIYRNTDFNNDGKPDNITFMIKRIKVHNMNAMKD-PSYRFPGNY- 556
            :..|.|..|..|:.::...|.||...:||  |..| |.|.||.:.|    ..:| ||......:
 Frog   223 RFNSIEQVISQISSYMTSVNAIYEQANFN--GIKD-INFKIKTLNV----VQEDKPSSAMHSTFI 280

  Fly   557 GVEKFLELFSEEDYDAFCLAYMFTYRDFEMGTLGLAWTGDLKNAGGVCEKNGHY---RGSLKSLN 618
            |.||.|.|.||..::.:||:|:.|.||:. |.|||||.|...|:||:|.|...|   ..:..:||
 Frog   281 GPEKLLMLHSESVWNNYCLSYLITDRDYN-GVLGLAWNGRPGNSGGICSKYSQYGENPNTFVTLN 344

  Fly   619 TGIVTLLNYGKHVPPAVSHVTLAHEIGHNFGSPHD-PEQCT---PGGEDGNFIMFARATSGDKKN 679
            |||||:..||:::||.:.|:|||||:||:.|:||| .|:|.   ....:||::||..|..|::.|
 Frog   345 TGIVTIQKYGQYLPPRLIHITLAHELGHSLGAPHDESEECARFDTTSPNGNYLMFPYAMDGNQYN 409

  Fly   680 NNKFSTCSLKSIEPVLNAKARSMKGCFTEPQSSICGNGVVEPGEQCDCGWEEDCKDSCCFPMSRQ 744
            |:|||:||:..|..:|..|...   ||.|.....|||.:||.|||||.|:.::  |.||:...
 Frog   410 NDKFSSCSIYYIGNLLRVKKDQ---CFVESDRPTCGNQIVEEGEQCDVGYNDN--DPCCYGAE-- 467

  Fly   745 PRLDETPCTLTPHARCSPSQGPCCTTDCK-LKFGDKCRDDNGCRDPSFCDGRVPQCPPSVNKPNK 808
               ....|||.|..:||||||.||:..|. :....:|:|:..|...:.|.|...:||..:.|.|.
 Frog   468 ---SALQCTLKPGKQCSPSQGLCCSHLCSYMPKSQRCQDEAECTLENNCTGDSAKCPKPLPKSNY 529

  Fly   809 TICN-KEFVCYMGDCTGSICLAYGLESCQCIPGPQDDRIKSCELCCKLPGEDSPCRS--SFE--- 867
            |:|| ...:|..|.|..|:|..:|||.|.|   ..:..::.|:|||:.|.....|:|  |.|
 Frog   530 TLCNLGTRICINGMCRQSVCAKFGLEQCDC---DSESMLEKCQLCCQEPDNVYSCKSTKSVELEH 591

  Fly   868 -WNEAPFDVPDMYSKPGTPCNDYNGYCDVFQKCREVDPSGPLATLRKLLLSEESIASFKKWMQHN 931
             :..|...:|     ||:||.:..||||.|..||.||..||:|.|:...|:...:.....||:..
 Frog   592 FFKRALLQLP-----PGSPCGNRQGYCDKFHICRLVDADGPIARLKNSFLNLIELEDPATWMKTR 651

  Fly   932 WYTVALAAVGVILLLALSTKLLAKRSNLKLKSVTIIHSATTETVRLPENNNGVIVHTAVR-TKVP 995
            |:.:.|    :||.||   .|:|        ....|...|.::.:..:.|......|..| ||:.
 Frog   652 WWAILL----IILTLA---ALMA--------GTVFIFGRTLDSDKEKQQNKEERRSTQQRSTKIV 701

  Fly   996 FKKK---VRGERTK 1006
            :.||   |:.|..|
 Frog   702 YCKKDDYVKAEYLK 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kul	NP_651716.1	Pep_M12B_propep	70..186	CDD:460254	30/119 (25%)
		ZnMc_TACE_like	479..713	CDD:239798	98/242 (40%)
		Disintegrin	720..801	CDD:459709	29/81 (36%)
LOC100491788	NP_001265673.1	ZnMc	208..439	CDD:469599	98/241 (41%)
		Disintegrin	447..523	CDD:459709	30/82 (37%)