DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kul and adam28.2

DIOPT Version :10

Sequence 1:NP_651716.1 Gene:Kul / 43501 FlyBaseID:FBgn0039688 Length:1537 Species:Drosophila melanogaster
Sequence 2:NP_001120446.1 Gene:adam28.2 / 100145537 XenbaseID:XB-GENE-5949648 Length:783 Species:Xenopus tropicalis


Alignment Length:495 Identity:131/495 - (26%)
Similarity:184/495 - (37%) Gaps:148/495 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   483 LYLQADHTFFQKMGSDEASIE-AITRHVQRANTIYRNTDFNNDGKPDNITFMIKRIKVHNMNAMK 546
            ||:.||.:.|.|.|....::: .|...|...|.:|         |..||...:..|:|.      
 Frog   201 LYMVADKSMFNKYGRSTENVKRRIFEIVNFVNVVY---------KQINIFVALTGIEVW------ 250

  Fly   547 DPSYRFPGNYGVEKFLELFSE---------EDYDAFCLAYMFTYRDFEMGTLGLAWTGDLKNAGG 602
            |.|..|......::.|:|||:         :.:|.   |...|:.||:..|:|||:.|.:     
 Frog   251 DKSDGFTVVSSADEDLKLFSDWRTKNLLPRKAHDN---AQFITHIDFDGSTVGLAYVGTM----- 307

  Fly   603 VCEKNGHYRGSLKSLNTGIVTLLNYGKHVPPAVS-HVTLAHEIGHNFGSPHDPEQCTPGGEDGNF 666
             |....         :||::.     .|...::: ..|:|||:|||.|..||...||  ...|:.
 Frog   308 -CSSTS---------STGVIQ-----DHSQQSIAIGATVAHEMGHNLGINHDEAHCT--CSTGSC 355

  Fly   667 IMFARATSGDKKNNNKFSTCSLKSIEPVLNAKARSMKGCF------TEPQS-SICGNGVVEPGEQ 724
            ||....:....:   :||.||.::.:..:..|   |..|.      ||.|: .:|||...|.||:
 Frog   356 IMEPALSFNTPR---EFSLCSHQNYQDFILQK---MPLCMKDVPKKTEIQTPPVCGNKFTELGEE 414

  Fly   725 CDCGWEEDCKDSCCFPMSRQPRLDETPCTLTPHARCSPSQGPCCTTDCK-LKFGDKCRDD-NGCR 787
            ||||...:|.:.||         :.|.|.|...|:|  ::|.||.: || .|.|..||.. :.|.
 Frog   415 CDCGSISECTNPCC---------NATTCKLKAGAQC--AEGQCCDS-CKWTKAGTVCRSKRHDCD 467

  Fly   788 DPSFCDGRVPQCPPSVNKPNKTIC-NKEFVCYMGDCTGSICLAYGLESCQCIPGPQ----DDRIK 847
            ....|||:..:||....:.|...| |.|..||.|.|.    ...||  |..:.||.    ||...
 Frog   468 LAEMCDGQSAECPSDRFRVNGFPCRNGEGYCYNGLCP----TLQGL--CSALWGPSSVVADDSCF 526

  Fly   848 SCEL-------CCKLPGEDSPCRSSFEWNEAPFDV-------PDMYSKP---------------- 882
            :..|       |....|...||:.|        ||       ...||.|                
 Frog   527 NYNLRGANNGYCQDSKGNQVPCKQS--------DVKCGVLYCSGGYSTPNLGGYYIRGECKTTLY 583

  Fly   883 -------GTPCND----YNGYCDVFQ----------KCRE 901
                   ||.|.|    :.|.|...|          ||.|
 Frog   584 PTFLVENGTKCGDNMVCFMGECTSIQTAFGPSDCDAKCPE 623

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KulNP_651716.1 Pep_M12B_propep 70..186 CDD:460254
ZnMc_TACE_like 479..713 CDD:239798 62/247 (25%)
Disintegrin 720..801 CDD:459709 29/82 (35%)
adam28.2NP_001120446.1 Pep_M12B_propep 33..151 CDD:460254
ZnMc_adamalysin_II_like 197..391 CDD:239797 59/235 (25%)
Disintegrin 410..482 CDD:459709 30/83 (36%)
ACR 487..608 CDD:214743 32/134 (24%)
PHA03247 <677..779 CDD:223021
Blue background indicates that the domain is not in the aligned region.

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