DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa40 and NAA40

DIOPT Version :9

Sequence 1:	NP_651715.1	Gene:	Naa40 / 43500	FlyBaseID:	FBgn0039687	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	XP_011543556.1	Gene:	NAA40 / 79829	HGNCID:	25845	Length:	300	Species:	Homo sapiens

Alignment Length:	181	Identity:	65/181 - (35%)
Similarity:	105/181 - (58%)	Gaps:	7/181 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NPLESLS-YQSYKAPSGEEFKLICRAKSDADSKLLKWAFKLAETNVGPYYKQLKMGWQPKIKAAE 87
            :|||:.. ::.|.. :|....:.|:..|..:...:.|||.|.:||:...|:|.:.||:.:.|..|
Human   100 DPLEAFPVFKKYDR-NGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGWKDREKREE 163

  Fly    88 LNKNWARYLVAQNEKKENVAYAMFRFDMDHGDCVLYCYEMQVAAEYRRKGLGKFIMSTLEDCARL 152
            :..:.|.||:|.......||::.||||::.||.||||||:|:.::.||||||||::..|:..|..
Human   164 MTDDRAWYLIAWENSSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANS 228

  Fly   153 WHLEKVMLTVLNNNEASISFFKQ-LGYVKDEISPDVL----EQADYQIFSK 198
            ..::||||||..:|..:..||:: |.:..|:.||.:.    |...|:|.|:
Human   229 TQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSR 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa40	NP_651715.1	Acetyltransf_1	106..179	CDD:278980	35/73 (48%)
NAA40	XP_011543556.1	Acetyltransf_1	180..250	CDD:278980	33/69 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153105
Domainoid	1	1.000	79	1.000	Domainoid score	I8710
eggNOG	1	0.900	-	-		E1_KOG2488
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41588
Inparanoid	1	1.050	121	1.000	Inparanoid score	I4759
Isobase	1	0.950	-	0	Normalized mean entropy	S5490
OMA	1	1.010	-	-		QHG57159
OrthoDB	1	1.010	-	-		D1489686at2759
OrthoFinder	1	1.000	-	-		FOG0004357
OrthoInspector	1	1.000	-	-		oto89725
orthoMCL	1	0.900	-	-		OOG6_102911
Panther	1	1.100	-	-	LDO	PTHR20531
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1911
SonicParanoid	1	1.000	-	-		X4736
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	18	17.750