DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa40 and Naa40

DIOPT Version :9

Sequence 1:	NP_651715.1	Gene:	Naa40 / 43500	FlyBaseID:	FBgn0039687	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_081919.1	Gene:	Naa40 / 70999	MGIID:	1918249	Length:	237	Species:	Mus musculus

Alignment Length:	189	Identity:	68/189 - (35%)
Similarity:	109/189 - (57%)	Gaps:	7/189 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VETAARAKNPLESLS-YQSYKAPSGEEFKLICRAKSDADSKLLKWAFKLAETNVGPYYKQLKMGW 79
            |:.|.|..:|||:.. ::.|.. :|....:.|:..|..:...:.|||.|.:||:...|:|.:.||
Mouse    29 VDAANRLGDPLEAFPVFKKYDR-NGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGW 92

  Fly    80 QPKIKAAELNKNWARYLVAQNEKKENVAYAMFRFDMDHGDCVLYCYEMQVAAEYRRKGLGKFIMS 144
            :.:.|..|:..:.|.||:|.......||::.||||::.||.||||||:|:.::.||||||||::.
Mouse    93 KDREKREEMTDDRAWYLIAWENSSIPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQ 157

  Fly   145 TLEDCARLWHLEKVMLTVLNNNEASISFFKQ-LGYVKDEISPDVL----EQADYQIFSK 198
            .|:..|....::||||||..:|..:..||:: |.:..|:.||.:.    |...|:|.|:
Mouse   158 ILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSR 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa40	NP_651715.1	Acetyltransf_1	106..179	CDD:278980	35/73 (48%)
Naa40	NP_081919.1	Acetyltransf_1	80..188	CDD:366181	45/107 (42%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q86UY6	127..129		1/1 (100%)
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q86UY6	140..142		0/1 (0%)
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q86UY6	148..153		4/4 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843204
Domainoid	1	1.000	79	1.000	Domainoid score	I8729
eggNOG	1	0.900	-	-		E1_KOG2488
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41588
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4771
Isobase	1	0.950	-	0	Normalized mean entropy	S5490
OMA	1	1.010	-	-		QHG57159
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004357
OrthoInspector	1	1.000	-	-		oto93295
orthoMCL	1	0.900	-	-		OOG6_102911
Panther	1	1.100	-	-	LDO	PTHR20531
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1911
SonicParanoid	1	1.000	-	-		X4736
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740