DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pcd and Pcbd2

DIOPT Version :9

Sequence 1:	NP_477360.2	Gene:	Pcd / 43499	FlyBaseID:	FBgn0024841	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	XP_006517461.1	Gene:	Pcbd2 / 72562	MGIID:	1919812	Length:	166	Species:	Mus musculus

Alignment Length:	165	Identity:	59/165 - (35%)
Similarity:	86/165 - (52%)	Gaps:	34/165 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 AAREAARAATGGSANLRRIHNTPTTEATATAITAKKRKMVVRLNEQERAEKLQPLLDAGWTLVEG 118
            ||...|.||.|..:..|.:....:..|:..|:::..:    .|..:||.:.:..|..|||:.:..
Mouse     3 AAAAVAVAAVGARSAGRWLAALRSPGASRAAMSSDAQ----WLTAEERDQLIPGLKAAGWSELSE 63

  Fly   119 RDAIFKQFVLKDFN------------------------------QAFSFMTGVALLAEKINHHPE 153
            ||||:|:|..|:||                              |||.||:.|||.|||:|||||
Mouse    64 RDAIYKEFSFKNFNQLHSLLPAPFWPAALEHFLRLWPPPWRLPSQAFGFMSRVALQAEKMNHHPE 128

  Fly   154 WFNCYNKVDVTLSTHDVGGLSSQDIRMATHLETTA 188
            |||.||||.:||::||.|||:.:|:::|..:|..|
Mouse   129 WFNVYNKVQITLTSHDCGGLTKRDVKLAQFIEKAA 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcd	NP_477360.2	PCD_DCoH_subfamily_b	112..186	CDD:238456	43/103 (42%)
Pcbd2	XP_006517461.1	PCD_DCoH_subfamily_b	57..162	CDD:238456	44/104 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845550
Domainoid	1	1.000	121	1.000	Domainoid score	I5690
eggNOG	1	0.900	-	-		E1_COG2154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4840
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002149
OrthoInspector	1	1.000	-	-		otm43144
orthoMCL	1	0.900	-	-		OOG6_100957
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2723
SonicParanoid	1	1.000	-	-		X2565
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.680