Protein Alignment dmrt99B and dmrta2

DIOPT Version :10

• Sequence 1: NP_524549.1
• Gene: dmrt99B / 43495
• FlyBaseID: FBgn0039683
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001007065.2
• Gene: dmrta2 / 474350
• ZFINID: ZDB-GENE-041116-2
• Length: 440
• Species: Danio rerio
• Alignment Length: 531
• Identity: 163/531 - (30%)
• Similarity: 215/531 - (40%)
• Gaps: 201/531 - (37%)

  Fly    24 PAFFLRAASERYQRTPKCARCRNHGVVSALKGHKRYCRWRDCVCAKCTLIAERQRVMAAQVALRR 88
            |...|| |:|:|.||||||||||||||||||||||||||:||:||||||||||||||||||||||
Zfish    43 PPLLLR-ATEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRR 106

  Fly    89 QQAQEENEARELGLLYTSVPGQQNGSDSATPTPHSPNHSGSGGSGSGGSGQNGVFHGGIPSPPSD 153
            ||||||||||||.|||.:                        ..|...:..||:.      ||..
Zfish   107 QQAQEENEARELQLLYGT------------------------AEGLALAAANGII------PPRQ 141

  Fly   154 GFE----ASSTPNHHQQSQQQQQAHHQQHLS---HPHQQSQRFNGNESDTDGRTRSEHLSVGFSP 211
            .:|    .|:..|..:.:.|:.:...:..|.   .|||.:    |....||  |.|   ..|.|
Zfish   142 NYEVFGPVSNESNSGESNIQKFELFPKTPLPGTVTPHQAA----GKSVSTD--TES---VPGMS- 196

  Fly   212 TRTELDESPVSKRGAALSNETDQDTGSESGSPSSPRPKVAGLFNLTASLSPARTGPPSSPESDLD 276
                   ||..:.|          :|||:|...|          :.:|       |.:.|..|
Zfish   197 -------SPDMRHG----------SGSENGDRES----------IVSS-------PIAKPLKD-- 225

  Fly   277 VDSAPDEATPENLSLKKEDSQSPPNTPAENLHLLRSFSSSHAQGFLPYHHTQFLAAAGLPAHHHP 341
                 .|.||.::|....||.|
Zfish   226 -----GEETPGSISPIGSDSGS------------------------------------------- 242

  Fly   342 AAHSPHHQQQQQQQQQQQNHLPQHHQQQQQQQQQQQRSPIDVLMRVFPNRRRSDVEQLMQRFRGD 406
                       ...:.:|...|       .....:|.:.||:|.|||||.:||.:|.::|....|
Zfish   243 -----------DTDKDEQEPSP-------SSAASRQMNAIDILTRVFPNHKRSVLELVLQGCGKD 289

  Fly   407 VLQAMECML--AGEDLG-------------------QTP-PQVPPSPPFPMKSAFSPLVP----- 444
            |:||:|.:|  :|:..|                   .|| |.:|.:.....:||||||.|
Zfish   290 VVQAIEQILNNSGQAKGPEETWTAERMLQSVQPTMSSTPRPMLPGTMTLSNRSAFSPLQPNAPHF 354

  Fly   445 ---PSVFGSPTH-RYHPF---MQAHAKRF-LTAPYAGTGYLPGV-------LSAADI-------- 486
               ||.:...|| ..:|.   ..||::.. ..|||:.||.:|.:       .:.:|:
Zfish   355 GSDPSTYPLSTHLGLNPLRLAYSAHSRGLAFMAPYSTTGLMPTLGFRPPMDYAFSDLIRDRTLLH 419

  Fly   487 -EQSESNGAGG 496
             :||.:||..|
Zfish   420 KDQSYTNGLYG 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmrt99B	NP_524549.1	DM	37..83	CDD:459924	43/45 (96%)
		CUE_DMA_DMRTA1	378..415	CDD:270600	17/36 (47%)
dmrta2	NP_001007065.2	DM	55..101	CDD:459924	43/45 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..261		32/205 (16%)
		CUE_DMA_DMRTA2	259..300	CDD:270601	19/40 (48%)
		DMRT5_DMB	340..426	CDD:466773	23/85 (27%)