DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmrt99B and dmd-9

DIOPT Version :9

Sequence 1:	NP_524549.1	Gene:	dmrt99B / 43495	FlyBaseID:	FBgn0039683	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_500305.1	Gene:	dmd-9 / 190512	WormBaseID:	WBGene00022060	Length:	254	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	52/303 - (17%)
Similarity:	88/303 - (29%)	Gaps:	120/303 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AASERYQRTPKCARCRNHGVVSALKGHKRYCRWRDCVCAKCTLIAERQRVMAAQVALRRQQAQEE 94
            ||.::..:...|.:|..||..:.||||...|.::||.|..|..:..    |.|...:||.:.::.
Worm    20 AAQKKAMKKLTCRKCEGHGTYAILKGHAGVCPYKDCSCGTCASVMS----MRANALIRRFRHRQP 80

  Fly    95 NEARELGLLYTSVPGQQNGSDSATPTPHSPNHS---GSGGSGSGGSGQNGVFHGGIPSPPSDGFE 156
            :::    :........:||:......|.:...:   ..|...:..|.:||
Worm    81 DQS----MAVVKALRSKNGNMRLRIVPRNDEETVVENDGTLVTYSSDKNG--------------- 126

  Fly   157 ASSTPNHHQQSQQQQQAHHQQHLSHPHQQSQRFNGNESDTDGRTRSEHLSVGFSPTRTELDESPV 221
                              ||.:                                        :..
Worm   127 ------------------HQTY----------------------------------------TTT 133

  Fly   222 SKRGAALSNETDQDTGSESGSPSSPRPKVAGLFNLTASLSPARTGPPSSPESDLD--VDSA---- 280
            ::|.:.::|.||......|..||:..       |.|.|.||    |...|..|:|  ||..
Worm   134 TRRSSIMTNSTDDRDSVVSTPPSTTN-------NSTPSGSP----PLLVPYGDVDIAVDPVGAAN 187

  Fly   281 -------------------PDEATPENLSLKKEDSQSPPNTPA 304
                               |...:|..:|...:.:|.|...|:
Worm   188 WEQITNIVRTTMLNQILMNPTNVSPALISFLLQPTQQPSFEPS 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmrt99B	NP_524549.1	DM	37..83	CDD:279137	14/45 (31%)
dmrt99B	NP_524549.1	CUE_DMA_DMRTA1	378..415	CDD:270600
dmd-9	NP_500305.1	DM	27..79	CDD:214606	17/55 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810