DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dmrt99B and dmd-10

DIOPT Version :9

Sequence 1:	NP_524549.1	Gene:	dmrt99B / 43495	FlyBaseID:	FBgn0039683	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001379162.1	Gene:	dmd-10 / 183202	WormBaseID:	WBGene00007929	Length:	348	Species:	Caenorhabditis elegans

Alignment Length:	277	Identity:	74/277 - (26%)
Similarity:	103/277 - (37%)	Gaps:	87/277 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 QRTPKCARCRNHGVVSALKGHKRYCRWRDCVCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 100
            :|.|.|.:|..||..|.||||||.|.:|:|.||||.:::|||::||.|:.:||:|.::
Worm   114 ERVPNCQKCGQHGRKSRLKGHKRSCPFRECPCAKCAVVSERQKLMADQIKIRRRQRKD------- 171

  Fly   101 GLLYTSVPGQQNGSDSATPTPHSPNHSGSGGSGSGGSGQNGVFHGGI---PSP----PSDGFEAS 158
             .|.|.      ..:|.|.|....|....       :..|.:.:|.|   |.|    |:....:|
Worm   172 -TLLTF------AKNSITSTMFPSNQISL-------NALNSLLYGSINTSPQPLLSSPTSSDASS 222

  Fly   159 STPNHHQQSQQQQQAHHQQHLSHPHQQS-QRFNGNESDTDGRTRSEHLSV-----GFSPTRTELD 217
            .:|                  |.|...| ..|....:|....|::...|:     ..||..|.|
Worm   223 CSP------------------SMPFTPSIPMFMPTSADCSPTTQTPTSSIPSSIASTSPLMTSL- 268

  Fly   218 ESPVSKRGAALSNETDQDTGSESGSPSSPRPKVAGLFNLTAS----------------LSPARTG 266
              |:...|..|.|..|         ||:.    |.|.||..:                |..|...
Worm   269 --PLRLSGFPLLNIRD---------PSAE----ASLLNLGCNADAAALLKTILDQYRMLEEASMS 318

  Fly   267 PPSSPESDLDVDSAPDE 283
            ..|||..|   |.:.||
Worm   319 MSSSPSKD---DESGDE 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmrt99B	NP_524549.1	DM	37..83	CDD:279137	25/45 (56%)
dmrt99B	NP_524549.1	CUE_DMA_DMRTA1	378..415	CDD:270600
dmd-10	NP_001379162.1	DM	39..92	CDD:214606
dmd-10	NP_001379162.1	DM	115..168	CDD:214606	28/52 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810