Protein Alignment dmrt99B and DMRT2

DIOPT Version :9

• Sequence 1: NP_524549.1
• Gene: dmrt99B / 43495
• FlyBaseID: FBgn0039683
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001374487.1
• Gene: DMRT2 / 10655
• HGNCID: 2935
• Length: 561
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 116/453 - (25%)
• Similarity: 156/453 - (34%)
• Gaps: 145/453 - (32%)

  Fly    30 AASERYQRTPKCARCRNHGVVSALKGHKRYCRWRDCVCAKCTLIAERQRVMAAQVALRRQQAQEE 94
            |...:..|||||||||||||||.||||||:||||||.||.|.|:.|||||||||||||||||.|:
Human   112 AEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATED 176

  Fly    95 NEARELGLLYTSVPGQQNGSDSAT---------------------PTPHSPNHSGSGGSGSGGSG 138
            .:         .:.|:||..:...                     |.|..
Human   177 KK---------GLSGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAE--------------- 217

  Fly   139 QNGVFHGG---IPSPPSDGF-EASSTPNHHQQSQQQQQAHHQQHLSHPHQQSQRFNGNESDTDGR 199
               .:.||   :|.|.||.. :..:..:...::...::.:.::.:....|.:..|..|.. ..|.
Human   218 ---TYVGGTFPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRM-VPGP 278

  Fly   200 TRSEHLSVGFSPTRTELDESPVSKRGAALSNETDQDTGSESGS-------------------PSS 245
            ..:.:.| .:||:..|    |.||............|...|||                   |.|
Human   279 DYNSYKS-AYSPSPVE----PPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLS 338

  Fly   246 PR----PKVAG----------LFNLTASLSPARTGP--------------------PSSPESDLD 276
            .|    ||...          |.|.|.|:...:.|.                    ||..|..|.
Human   339 SRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQDMMPSKLEGSLV 403

  Fly   277 VDSAPDEATPENLSLKKEDSQSPPNTPAENLHLLRSFSSSHAQGFLPYHHTQFLAAAG------- 334
            :...|:      :...:.|.|.....|.      ||..|...:.|.|...|..|||.|
Human   404 LPHTPE------IQTTRSDLQGHQAVPE------RSAFSPPRRNFSPIVDTDSLAAQGHVLTKIS 456

  Fly   335 --LPAHHHPAAHSPHHQQQQQQQQQQQ-------------NHLPQHHQQQQQQQQQQQRSPID 382
              ...|..|..|:|.|...||....:.             ...|:.|::...:..|:....||
Human   457 KENTRHPLPLRHNPFHSLFQQTLTDKSGPELKTPFVKEAFEETPKKHRECLVKDNQKYTFTID 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmrt99B	NP_524549.1	DM	37..83	CDD:279137	38/45 (84%)
		CUE_DMA_DMRTA1	378..415	CDD:270600	2/5 (40%)
DMRT2	NP_001374487.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..119		1/6 (17%)
		DM	119..165	CDD:395608	38/45 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	414..435		6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810