DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gycalpha99B and Gucy2g

DIOPT Version :9

Sequence 1:NP_477088.2 Gene:Gycalpha99B / 43493 FlyBaseID:FBgn0013972 Length:676 Species:Drosophila melanogaster
Sequence 2:NP_001074545.1 Gene:Gucy2g / 73707 MGIID:106025 Length:1100 Species:Mus musculus


Alignment Length:259 Identity:100/259 - (38%)
Similarity:139/259 - (53%) Gaps:38/259 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   408 DGLRRRMDKIKNSIEEANSAVTK----ERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTIL 468
            |.:..:::...|.:||.....|:    |::|...||..:.|:.:.|:|..|.|::.:.:..|||.
Mouse   839 DSMMGKLETYANHLEEVVEERTRELVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIF 903

  Fly   469 FSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLH-RASIYDAH 532
            ||||||||.:||.::|..|:.:|..||..||......||||||||||||.|||||. |.....|.
Mouse   904 FSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQSHDVYKVETIGDAYMVASGLPIRNGAQHAD 968

  Fly   533 KVAWMALKMIDACSK-HITH-DGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESG 595
            ::|.|||.::...:. .|.| ..|::|:|||||||.|:|||||..||||||||.:|.:|::.||.
Mouse   969 EIATMALHLLSVTTHFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESS 1033

  Fly   596 SEALKINVSPTTKD---------------------------WLTKHEGFEFELQPRDPSFLPKE 632
            |..|:|:||.:|..                           ||...:||...|    |.|..:|
Mouse  1034 SLPLRIHVSQSTAGALLAAGGYHLQKRGTISVKGKGEQTTFWLKGKDGFPVPL----PEFTEEE 1093

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gycalpha99BNP_477088.2 HNOB 76..208 CDD:285002
HNOBA 259..451 CDD:285003 11/46 (24%)
CYCc 430..619 CDD:214485 91/222 (41%)
Guanylate_cyc 457..647 CDD:278633 86/206 (42%)
Gucy2gNP_001074545.1 PBP1_GC_G-like 47..436 CDD:380595
PK_GC 555..829 CDD:270894
CYCc 865..1055 CDD:214485 87/189 (46%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.