Protein Alignment Gycalpha99B and adcy6b

DIOPT Version :9

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_002666536.2
• Gene: adcy6b / 560807
• ZFINID: ZDB-GENE-090127-2
• Length: 1174
• Species: Danio rerio
• Alignment Length: 476
• Identity: 107/476 - (22%)
• Similarity: 197/476 - (41%)
• Gaps: 106/476 - (22%)

  Fly   216 RRYRYLFSLVKDNSQTMLMGRPTSVSKTI---------PETVQRSNSSNASDLQM------NSSS 265
            |.|:..|..:..:|.|||||....|...:         |:....|..|.|..|.:      |.:.
Zfish   146 RLYQRYFFRLNQSSLTMLMGVLVVVCGVMLAFHCVQGPPDVAYASVLSVAMGLFLTLMVVCNRNG 210

  Fly   266 FCKMFPW--HFIMNEQLELVQLGRGFSKLYKPYMADFGCQATTYFDFKRPKGLTMKFRDIVRRTY 328
            |.:.:.|  .:::...|.:||: .|...:..|.|.: |...|.:|.:             :..|.
Zfish   211 FHQDYMWIVSYLVMGVLVVVQV-FGLLMVDPPSMPE-GIWWTVFFIY-------------IIYTL 260

  Fly   329 TPFLIGLNNPPGAV-----DFPAIGLEIKGQMVH---CPESNSLLFIGSPFLDGLDGLTCNGLFI 385
            .|..:......|||     ...|....::...::   |  :|:::|:            |.
Zfish   261 LPVRMRAAVITGAVLSTIHIVMAWRFNLEDSFLYKQLC--ANAMIFL------------CT---- 307

  Fly   386 SDIPLHDATREVILVGEQARAQDGLRRRMDKIKNSIEEANSAVTKERKKNVSLLHLIFPAEIAEK 450
                      .:|.:.....|:...|:...:.:..| :|...:.:|.::...||..:.|..:|
Zfish   308 ----------NIIGICTHYPAEVSQRQAFKETRGYI-QARIHLQRENQQQERLLLSVLPRHVA-- 359

  Fly   451 LWLGSSIDAK------------TYPDVTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCD 503
            :.:.:.|:||            .:.:|:|||:||.||||:.|:.|...::..|..|:..||:...
Zfish   360 MEMKADINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAW 424

  Fly   504 FFDVYKVETIGDAYCVASGLHRASIYDAHKVAWMALKMIDACS--KHITHDGEQIKMRIGLHTGT 566
            .....:::.:||.|...|||.......||....|.:.||:|.|  :.:|  |..:.||:|:|:|.
Zfish   425 ENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVT--GVNVNMRVGIHSGR 487

  Fly   567 VLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINVSPTTKDWLTKHEGFEFELQPRDPSFLPK 631
            |..||:|.:..::.::.:.||:||:.|:|.:|.:|:::..|..:|..    ::|:   :..|
Zfish   488 VHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAGRIHITKATLQYLNG----DYEV---EAGF--- 542

  Fly   632 EFPNPGGTETCYF----LESF 648
                 ||....|.    :|:|
Zfish   543 -----GGDRNAYLNNNNIETF 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002
		HNOBA	259..451	CDD:285003	33/207 (16%)
		CYCc	430..619	CDD:214485	58/202 (29%)
		Guanylate_cyc	457..647	CDD:278633	58/207 (28%)
adcy6b	XP_002666536.2	AC_N	15..376	CDD:318454	50/275 (18%)
		Guanylate_cyc	378..562	CDD:306677	57/198 (29%)
		DUF1053	590..677	CDD:310728
		Guanylate_cyc	975..1169	CDD:306677

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900