Protein Alignment Gycalpha99B and NPR3

DIOPT Version :9

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001191304.1
• Gene: NPR3 / 4883
• HGNCID: 7945
• Length: 541
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 95/501 - (18%)
• Similarity: 156/501 - (31%)
• Gaps: 163/501 - (32%)

  Fly   192 LKALTRMLYKVDVNIKIEPVEGDARRY------------------RYLFSLVKDNSQTMLMGRPT 238
            |.:|||:...::..::.....|..||.                  |.||||| |........:|.
Human    66 LFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLV-DRVAAARGAKPD 129

  Fly   239 SVSKTIPETVQRSNSSNAS--DLQMNS---------------SSFCKMFPWHFIMNEQLELVQLG 286
            .:...:.|......:..||  ||.|.|               |...::.|.:..|.|.:..:...
Human   130 LILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRH 194

  Fly   287 RGFSKLYKPYMAD-------FGCQA-----------TTYFDFKRPKGLTMKFRDIVRRTYTPFLI 333
            ..:|:....|..|       |..:.           |:.:.|...|.|.::  ||||.......:
Human   195 HHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLE--DIVRNIQASERV 257

  Fly   334 GLNNPPGAVDFPAIGLEIKGQMVHCPESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVI 398
                                 ::.|..|:::..|  ..:....|:|.......:|.|.::
Human   258 ---------------------VIMCASSDTIRSI--MLVAHRHGMTSGDYAFFNIELFNS----- 294

  Fly   399 LVGEQARAQDGLRRRMDKIKNSIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSID----- 458
                 :...||..:|.||.....::|.|::     :.|:||..:.|......:.:.||::
Human   295 -----SSYGDGSWKRGDKHDFEAKQAYSSL-----QTVTLLRTVKPEFEKFSMEVKSSVEKQGLN 349

  Fly   459 --------AKTYPDVTIL-----------------------------FSDIVGFTSICS---RAT 483
                    .:.:.|..:|                             |..|.|..||.:   |..
Human   350 MEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYG 414

  Fly   484 PFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAHKVAWMALKM-IDACSK 547
            .|.||:|.:            .:....|.||| |....|  |..:....|..|..||: ||. ::
Human   415 DFSVIAMTD------------VEAGTQEVIGD-YFGKEG--RFEMRPNVKYPWGPLKLRIDE-NR 463

  Fly   548 HITH-DGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKF 592
            .:.| :....|...||....|...|||      .|.|..:.:|..|
Human   464 IVEHTNSSPCKSSGGLEESAVTGIVVG------ALLGAGLLMAFYF 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002	4/15 (27%)
		HNOBA	259..451	CDD:285003	37/224 (17%)
		CYCc	430..619	CDD:214485	43/210 (20%)
		Guanylate_cyc	457..647	CDD:278633	37/183 (20%)
NPR3	NP_001191304.1	PBP1_NPR_C_like	54..446	CDD:107381	77/435 (18%)
		ANF_receptor	71..422	CDD:279440	66/391 (17%)
		TM_EphA1	476..507	CDD:214014	10/34 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900