Protein Alignment Gycalpha99B and Gyc89Da

DIOPT Version :10

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Alignment Length: 689
• Identity: 152/689 - (22%)
• Similarity: 283/689 - (41%)
• Gaps: 178/689 - (25%)

  Fly    87 KSCANYDYLADIQELLLKMDEASASEILVLLGEELITCC------CTGIIERAF----------- 134
            |.|    ::.|.:....|..:....:::..:.|.|..|.      |.....|.|
  Fly    24 KVC----HIIDCKHNSFKTHQIYPDKLMPDIAEALSACTGESFDFCMNFFGRCFVRFFSNFGYDK 84

  Fly   135 --RCLGTDLQEFLGSLDGVYDVLK----------LQEEDVTDTGFVCAGEGELIFTSERPVIAWL 187
              |..|....:||.|:|.::.:::          :|..::.|.|.|      :::.|.|..::..
  Fly    85 MIRSTGRYFCDFLQSIDNIHLIMRFTYPKMKSPSMQLTNMDDNGAV------ILYRSSRTGMSKY 143

  Fly   188 LLGSLKALTRMLYKVDVNIKIEPVEGDAR------------------RYRYLFSLVKDNSQTMLM 234
            |:|.:..:.|..|.:::...:...:.|..                  :||..|    ||.:.|
  Fly   144 LIGQMTEVAREFYGLEIKAYVIESQNDISGGTAGPIKLTDGPLTVIVKYRLDF----DNREYM-- 202

  Fly   235 GRPTSVSKTIPETVQRSNS-SNASDLQMNS---SSFCKMFPWHFIMNEQLELVQLGRGFSKLYKP 295
                         .:|.|: ::.|.|:|.:   ..|..:||:.|::|..:::...|   .|:.:.
  Fly   203 -------------AKRVNTEAHPSQLKMPTVKLDVFLDLFPFTFVLNHDMKITHAG---EKIVET 251

  Fly   296 YM---------ADFGCQATTYFDFKRPKGLTMKFRDIVRRTYTPF---LIGLNNPPGA------V 342
            ::         :..|......|..:|||..|:.:..:::.....|   ||...:...|      :
  Fly   252 WIMHNPGANPKSFIGTHVMDLFQCRRPKDTTIDWDTLIQMRAVLFEFELIRTGHNRAAYDAVLNM 316

  Fly   343 DF----------------------------------------PAIG----------LEIKGQMVH 357
            ||                                        ||.|          :.:||||.:
  Fly   317 DFENYDEMDLNEAQTMALAKAQEFSESHPVDDDESAREDEIDPATGERRSSQGLRSILLKGQMFY 381

  Fly   358 CPESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVILVGEQARAQ-----DGLRRRMDKI 417
            ..:.:||:|:.||.::.||.|...||:::|:..|..:||:::.|.|..::     :...:|.|::
  Fly   382 IKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDEL 446

  Fly   418 KNSIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTILFSDIV-----GFTS 477
            :.|:|.|:|    .:::...||:.:.|..|||::.|......:::.:|:::|.:::     |..|
  Fly   447 EKSLELADS----WKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNS 507

  Fly   478 ICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAHKVAWMALKMI 542
            |   ......::.|..::...||......||||||:|..|...||....:...|.....:||:::
  Fly   508 I---QGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPLHAEHACDLALRVM 569

  Fly   543 DACSKHITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINVSPTT 607
               .|...||...:.:|:|:::|.|:|||||:|:|||||||.:|..|::.||.|:..||.:|..|
  Fly   570 ---KKFKAHDMGDVAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYT 631

  Fly   608 KDWLTKHEGFEFELQPRDPSFLPKEFPNPGGTETCYFLE 646
            .| ..:..|::.|      |....:....|..||.:.||
  Fly   632 GD-KVRQVGYKVE------SRGTVQVKGKGDMETYWLLE 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	<109..208	CDD:462233	22/127 (17%)
		HNOBA	259..451	CDD:462234	56/267 (21%)
		Guanylate_cyc	457..647	CDD:425528	59/195 (30%)
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233	26/146 (18%)
		HNOBA	218..476	CDD:462234	54/264 (20%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	57/189 (30%)