DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gycalpha99B and CG32305

DIOPT Version :9

Sequence 1:	NP_477088.2	Gene:	Gycalpha99B / 43493	FlyBaseID:	FBgn0013972	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_728725.2	Gene:	CG32305 / 317967	FlyBaseID:	FBgn0052305	Length:	1164	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	77/295 - (26%)
Similarity:	134/295 - (45%)	Gaps:	49/295 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 EVILVGEQARAQDGLRRRMDKIKNSIEEANSAVTKERKKNVSLLHLIFPAEIA-EKLWLGSSIDA 459
            ::::..|....:..|.|:|  |:...||..|.: :::.||.:      |::.. .||:|
  Fly   242 QLVMKKENGLLESILPRKM--IRTLQEEICSRI-EDQDKNFT------PSKAGLRKLFL------ 291

  Fly   460 KTYPDVTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLH 524
            :.||:|:||.:|:|.:|.:.:......::.:|..|:.:||...:.....:::.:||:|...:|:
  Fly   292 EPYPNVSILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGDSYNCVAGI- 355

  Fly   525 RASIYDAHKVAWM--ALKMIDACSKHITHDGE-----QIKMRIGLHTGTVLAGVVGRKMPRYCLF 582
             .:.:.||....:  ||:||     |||....     .|.:|||:|:|.|.||::|....::.::
  Fly   356 -PNYFPAHASCCVDQALEMI-----HITQGVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIW 414

  Fly   583 GHSVTIANKFESGSEALKINVSPTTKDWLTKHEGFE--FELQPRDPSFLPKEFPNPGGTETCYFL 645
            ...|.|.|:.||......::||..|...|.:|..|.  .|....||..      ...|..|  ||
  Fly   415 SKDVDITNRLESSGLPGLVHVSQRTLSMLDEHYIFREGTEAAKNDPIL------QQAGIRT--FL 471

  Fly   646 ESFRNP------ALDSELPLVEHINVSMKTISEGG 674
            .|.|.|      .||.||   ...:::...:|.||
  Fly   472 VSNRLPDAVEPGELDDEL---SSASINSCRLSYGG 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002
		HNOBA	259..451	CDD:285003	11/55 (20%)
		CYCc	430..619	CDD:214485	52/198 (26%)
		Guanylate_cyc	457..647	CDD:278633	53/198 (27%)
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	58/219 (26%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	44/159 (28%)
		CYCc	814..1056	CDD:214485
		Nucleotidyl_cyc_III	845..1081	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453924
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740