DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gycalpha99B and Gucy2g

DIOPT Version :9

Sequence 1:NP_477088.2 Gene:Gycalpha99B / 43493 FlyBaseID:FBgn0013972 Length:676 Species:Drosophila melanogaster
Sequence 2:NP_620611.2 Gene:Gucy2g / 245708 RGDID:621853 Length:1103 Species:Rattus norvegicus


Alignment Length:250 Identity:98/250 - (39%)
Similarity:136/250 - (54%) Gaps:34/250 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   417 IKNSIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTILFSDIVGFTSICSR 481
            ::..:||....:..|::|...||..:.|:.:.|:|..|.|::.:.:..|||.||||||||.:||.
  Rat   855 LEEVVEERTCQLVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSL 919

  Fly   482 ATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLH-RASIYDAHKVAWMALKMIDAC 545
            ::|..|:.:|..||..||......||||||||||||.|||||. |.....|.::|.|:|.::...
  Rat   920 SSPLQVVKLLNDLYSLFDHTIQTHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMSLHLLSVT 984

  Fly   546 SK-HITH-DGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINVSPTTK 608
            :. .|.| ..|::|:|||||||.|:|||||..||||||||.:|.:|::.||.|..|:|:||.:|.
  Rat   985 TNFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTA 1049

  Fly   609 D---------------------------WLTKHEGFEFELQPRDPSFLPKEFPNP 636
            .                           |||..:||...|    |.|..:|...|
  Rat  1050 RALLVAGGYHLQKRGTISVKGKGEQTTFWLTGKDGFAVPL----PEFTEEEAKVP 1100

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gycalpha99BNP_477088.2 HNOB 76..208 CDD:285002
HNOBA 259..451 CDD:285003 8/33 (24%)
CYCc 430..619 CDD:214485 91/218 (42%)
Guanylate_cyc 457..647 CDD:278633 86/209 (41%)
Gucy2gNP_620611.2 PBP1_GC_G_like 50..439 CDD:107367
ANF_receptor 66..417 CDD:279440
PK_GC 558..832 CDD:270894
CYCc 868..1058 CDD:214485 86/189 (46%)
Guanylate_cyc 895..1081 CDD:278633 79/185 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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