DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gycalpha99B and Adcy5

DIOPT Version :9

Sequence 1:NP_477088.2 Gene:Gycalpha99B / 43493 FlyBaseID:FBgn0013972 Length:676 Species:Drosophila melanogaster
Sequence 2:NP_001012783.3 Gene:Adcy5 / 224129 MGIID:99673 Length:1262 Species:Mus musculus


Alignment Length:304 Identity:76/304 - (25%)
Similarity:141/304 - (46%) Gaps:53/304 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   375 LDGLTCNGLFISDIPLHDATREVILVGEQAR------------------AQDGLRRRMDKIKNSI 421
            |.|:..:.|.:: |.||..:::..|:.:...                  |:...|:...:.:..|
Mouse   353 LSGVLLSALHLA-ISLHTNSQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECI 416

  Fly   422 EEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAK------------TYPDVTILFSDIVG 474
             :|.....:|.::...||..:.|..:|  :.:.:.|:||            .:.:|:|||:||.|
Mouse   417 -QARLHSQRENQQQERLLLSVLPRHVA--MEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEG 478

  Fly   475 FTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAHKVAWMAL 539
            |||:.|:.|...::..|..|:..||:........:::.:||.|...|||..|....||....|.:
Mouse   479 FTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM 543

  Fly   540 KMIDACS--KHITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKIN 602
            .||:|.|  :.:|  |..:.||:|:|:|.|..||:|.:..::.::.:.||:||..|:|.:|.:|:
Mouse   544 DMIEAISLVREVT--GVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIH 606

  Fly   603 VSPTTKDWLTKHEGFEFELQPRDPSFLPKEFPNPGGTETCYFLE 646
            ::..|.::|..    ::|::           |..||....|..|
Mouse   607 ITKATLNYLNG----DYEVE-----------PGCGGDRNAYLKE 635

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gycalpha99BNP_477088.2 HNOB 76..208 CDD:285002
HNOBA 259..451 CDD:285003 16/93 (17%)
CYCc 430..619 CDD:214485 59/202 (29%)
Guanylate_cyc 457..647 CDD:278633 60/204 (29%)
Adcy5NP_001012783.3 AC_N 1..459 CDD:292831 19/109 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..194
CYCc 425..620 CDD:214485 59/202 (29%)
Guanylate_cyc 461..622 CDD:278633 52/166 (31%)
DUF1053 669..761 CDD:283888
CYCc 1037..1238 CDD:214485
Guanylate_cyc 1063..1257 CDD:278633
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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