Protein Alignment Gycalpha99B and gcy-36

DIOPT Version :9

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_510557.3
• Gene: gcy-36 / 191657
• WormBaseID: WBGene00001556
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 625
• Identity: 157/625 - (25%)
• Similarity: 283/625 - (45%)
• Gaps: 98/625 - (15%)

  Fly    82 DPQTFKSCANYDYLADIQELLLKMDEASASEILVLLGEELITCCCTGIIERAFRCLGTDLQEFLG 146
            |..||.       |.|...::||:   :..::..:.|..||........:...|.:..:|:.||.
 Worm    45 DADTFS-------LVDAVSVILKV---TREQVWEMYGCFLIQYTMETGWDDLIRSMSPNLKGFLD 99

  Fly   147 SLDGVYDVLK--LQEEDVTDTGFVCA----GEGELIFTSERPVIAWLLLGSLKALTRMLYKVDVN 205
            :||.::..:.  :.:.::....|.|.    |...|.:.:.||.:..::.|.|:...:.::|:||:
 Worm   100 NLDSLHYFIDHVVYKANLRGPSFRCEDNPDGTITLHYYTGRPGLYPIVKGVLREAAKRVFKLDVS 164

  Fly   206 I--------KIEPVEGDARRYRYLFSLVK----DNSQTMLMGRPTSVSKTIPETVQRSNSSNASD 258
            :        .::...|: |...::..|||    |.|....:|  |:|       ||.||:..
 Worm   165 MTITGRTQRSVQMATGE-RIEEHVIFLVKTLNTDQSNEEALG--TAV-------VQHSNNYK--- 216

  Fly   259 LQMNSSSFCKMFPWHFIMNEQLELVQLGRGFSKLYKPYMADF---GCQATTYFDFKRPKGLTMKF 320
            :::....|...||:|.::::..::||:||   :||.....|.   |......|:..||: :.:.|
 Worm   217 IRLTHMDFISTFPYHMVVDQDCKIVQVGR---ELYNHIPKDLLSVGTPLMRIFEVTRPQ-IPLDF 277

  Fly   321 RDIVRRTYTPFLIGLNNPP--------------------------GAVDFPAIG----LEIKGQM 355
            ..|.......|::.:...|                          ||:   |:.    |::||||
 Worm   278 DSICNFINAVFVLQVKTTPMEFQRNANKRAAQAIEASENLYEDNNGAL---ALSQSQHLKLKGQM 339

  Fly   356 VHCPESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVILVGEQARAQDGLRRRMDKIKNS 420
            :.......::::.||::..:..|...||.::.:|:||.||::||:.:|..:...:..:::.....
 Worm   340 MLMSSGGHIMYLCSPYVTSIPELLQYGLRLTAMPIHDPTRDLILLNQQRLSDVEMNLQLEANNEQ 404

  Fly   421 IEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTILFSDIVGFTSICSRATPF 485
            :|.....:..|:.|..:||..:.|..:|::|..|.|::|:.|.:.|::|:|:..|..|....||.
 Worm   405 LENMAKDLEVEKGKTDALLREMLPPSVAQQLKQGLSVEAREYEEATVMFTDVPTFQQIVPLCTPK 469

  Fly   486 MVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAH--KVAWMALKMI----DA 544
            .::.:|..|:..||........|||||:||:|....|:  ..:.|.|  .:..:||.|:    ..
 Worm   470 DIVHLLNELFTKFDRLIGIQKAYKVETVGDSYMSVGGI--PDLVDDHCEVICHLALGMVMEARTV 532

  Fly   545 CSKHITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINVSPTTKD 609
            |.. ||:  ..:.:|.|:|:|.|:|||||.|||||||||.:|..:::.||.|...:|:.|...|.
 Worm   533 CDP-ITN--TPLHIRAGIHSGPVVAGVVGAKMPRYCLFGDTVNTSSRMESHSPIGRIHCSENAKK 594

  Fly   610 WLTKHEGFEFELQPRDPSFLPKEFPNPGGTETCYFLESFR 649
            .......||||.:.|      .:....|...|.:.|.||:
 Worm   595 CAESTGRFEFEPRGR------VQIKGKGEMNTYFLLRSFK 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002	27/139 (19%)
		HNOBA	259..451	CDD:285003	47/224 (21%)
		CYCc	430..619	CDD:214485	66/194 (34%)
		Guanylate_cyc	457..647	CDD:278633	64/195 (33%)
gcy-36	NP_510557.3	HNOB	3..167	CDD:285002	27/131 (21%)
		HNOBA	217..435	CDD:285003	47/224 (21%)
		CYCc	415..604	CDD:214485	66/193 (34%)
		Guanylate_cyc	441..624	CDD:278633	63/193 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820