Protein Alignment Gycalpha99B and gcy-25

DIOPT Version :9

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001294116.1
• Gene: gcy-25 / 191653
• WormBaseID: WBGene00001549
• Length: 1034
• Species: Caenorhabditis elegans
• Alignment Length: 432
• Identity: 92/432 - (21%)
• Similarity: 175/432 - (40%)
• Gaps: 118/432 - (27%)

  Fly   249 QRSN-----SSNASDLQMNSSSFCKMFPWHFIMNEQLELVQLGRG-------------FSKLYKP 295
            :|:|     .|:|.|:......:.::.|.|  ::..||.::..||             :..|:
 Worm   619 ERTNHKELAPSSAFDVDAIHYKYLQLAPEH--ISAILEKLEEPRGTVEGDIYQLAMCIYQILF-- 679

  Fly   296 YMADF--------------GCQATTYFDFKRPKG--LTMKFRDIVRRTY------TPFLIGLNNP 338
            ||..|              ..|:|.....|.|:|  .||:...|:::.:      .|.||.:.:
 Worm   680 YMRPFAERQESIKELAHLLSSQSTAPLHPKVPEGNSFTMRLLSIIQQCWLYKPAARPALIKITD- 743

  Fly   339 PGAVDFPAIGLEIKGQMVHCPESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVILVGEQ 403
              ||: ...|.::||.::
 Worm   744 --AVN-REFGQDVKGTLI----------------------------------------------- 758

  Fly   404 ARAQDGLRRRMDKIKNSIEEANSAVTKERKKNVS----LLHLIFPAEIAEKLWLGSSIDAKTYPD 464
                |.:...:|:...::|:..:..|:|.::::|    ||:.:.|..:|:.:..|.::..:.:..
 Worm   759 ----DQMIEMIDEYSANLEQIVAERTRELEQDMSVTENLLYQLLPKSVADSIRSGKTVVPEQHSS 819

  Fly   465 VTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIY 529
            ||:|..|:..||..|....|..::..|:.||..||........:|||.:||||.:.||:...|.:
 Worm   820 VTLLVVDVCQFTKFCEAFIPVHILETLQELYSSFDNIVQKNKAFKVENVGDAYLICSGIPEMSGF 884

  Fly   530 -DAHKVAWMALKMIDACSK--HITH-DGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIAN 590
             ...::..::|| :.|..|  .:.| ....:::::|:.:|.|.||::|...||:|:||.:|.:|.
 Worm   885 RHLREICKISLK-LQAFMKTFKVRHRPSHTLQIKMGITSGAVAAGILGSTAPRFCIFGDTVNMAC 948

  Fly   591 KFESGSEALKINVSPTTKDWLTKHEGFEFELQPRDPSFLPKE 632
            :..|......|.:|..|.:          .|..:.|||:.:|
 Worm   949 RMASTGNPGSIQLSELTAN----------TLMEKFPSFMLEE 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002
		HNOBA	259..451	CDD:285003	36/230 (16%)
		CYCc	430..619	CDD:214485	52/196 (27%)
		Guanylate_cyc	457..647	CDD:278633	50/180 (28%)
gcy-25	NP_001294116.1	PBP1_iGluR_N_LIVBP_like	56..>230	CDD:107346
		PKc_like	473..746	CDD:304357	27/133 (20%)
		SPS1	474..>736	CDD:223589	23/120 (19%)
		HNOBA	<764..805	CDD:285003	9/40 (23%)
		CYCc	790..976	CDD:214485	52/196 (27%)
		Nucleotidyl_cyc_III	812..999	CDD:299850	50/180 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810