Protein Alignment Gycalpha99B and gcy-3

DIOPT Version :10

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_496037.1
• Gene: gcy-3 / 191641
• WormBaseID: WBGene00001530
• Length: 1140
• Species: Caenorhabditis elegans
• Alignment Length: 280
• Identity: 92/280 - (32%)
• Similarity: 142/280 - (50%)
• Gaps: 48/280 - (17%)

  Fly   385 ISDIPLHDATREVILVGEQARAQ------------DGLRRRMDKIKNS----------------- 420
            |:|:|  |....:|.:.:...|:            :.||..|.|.|::
 Worm   787 ITDVP--DVNPTLIALVKDCWAEAPEDRPTAENICEQLRDLMPKTKSNLMDHVFNMLEEYTSTLE 849

  Fly   421 --IEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTILFSDIVGFTSICSRAT 483
              :||....:|.|:||...||..:.|.::||:|..|.:::.:.:..||:.|||:|.||.:.|:.|
 Worm   850 VEVEERTKELTLEKKKADLLLSRMLPKQVAERLKAGQTVEPEGFDSVTVFFSDVVKFTILASKCT 914

  Fly   484 PFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGL-------HRASIYDAHKVAWMALKM 541
            ||.|:::|..||.:||...:...|||||:|||.|...|||       |...|.|      |:||.
 Worm   915 PFQVVNLLNDLYSNFDTIIEEHGVYKVESIGDGYLCVSGLPTRNGFNHIKQIVD------MSLKF 973

  Fly   542 IDACSK-HITH-DGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINVS 604
            :|.|.. .|.| ..|::::|||:::|..:|||||..||||||||.:|..|::.||..:...|:::
 Worm   974 MDYCKNFKIPHLPRERVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSLIHLT 1038

  Fly   605 PTTKDWLTKHEGFEFELQPR 624
            ......|.||...::|...|
 Worm  1039 SDAHLLLMKHFPHQYETNSR 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	<109..208	CDD:462233
		HNOBA	259..451	CDD:462234	22/96 (23%)
		Guanylate_cyc	457..647	CDD:425528	68/177 (38%)
gcy-3	NP_496037.1	PBP1_NPR_GC-like	36..452	CDD:380575
		Protein Kinases, catalytic domain	554..823	CDD:473864	6/37 (16%)
		HNOBA	<838..882	CDD:462234	11/43 (26%)
		CYCc	861..1051	CDD:214485	76/195 (39%)