Protein Alignment Gycalpha99B and odr-1

DIOPT Version :10

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001362115.1
• Gene: odr-1 / 181479
• WormBaseID: WBGene00003848
• Length: 1047
• Species: Caenorhabditis elegans
• Alignment Length: 723
• Identity: 151/723 - (20%)
• Similarity: 261/723 - (36%)
• Gaps: 197/723 - (27%)

  Fly    26 WALEDEELSDDALT-------LTHLQMAIQLLTAPSNEDLNTAVTSLVAKYRQNWPNIHKL--KL 81
            |.|:|.:..||.:.       :.|:..|:.::|      :......::.|.|::..||:||  |:
 Worm   398 WTLKDMDPPDDCVAKSSCVNYIPHIIAAVVIVT------IIVIAIVIIVKQRRHKLNIYKLTWKV 456

  Fly    82 DPQTFKSCANYDYLADIQELLLKMDEASASEILVLLGEELITCCCTGIIER-----AFRCLGTDL 141
            ..::.|...|.:..|.:|..|    |..||.          |.....:..|     ::..:||..
 Worm   457 PKESLKIIVNKNADAKMQREL----ENRASN----------TDNAAALTSRRRVFGSYALVGTQR 507

  Fly   142 QEFL------------GSLDGVYDVLKLQEEDVTDTGFVCAGEGELIFTSERPVIAWLLLGSLKA 194
            .|::            .:||.:|.:.:||.:::.
 Worm   508 AEYVQFKQIRKINFPETTLDYLYSLKQLQHDNLA------------------------------- 541

  Fly   195 LTRMLYKVDVNIKIEPVEGDARRYRYLFSLVKDNS-QTMLMGRPTSVSKTIPETVQRSNSSNASD 258
               ..|.:.||       .|......|.:||:..: :...:.|...:..|......|........
 Worm   542 ---KFYGIQVN-------DDIMTMTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQY 596

  Fly   259 LQMNS--------SSFCKM-FPWHF---------IMNEQL--ELVQLGRGFSKL--YKPYMADFG 301
            |..:|        :|.|.: ..|..         .|::||  |.:::....:.:  |..|:....
 Worm   597 LHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKVPEQAAHMITYPQYVCFPP 661

  Fly   302 CQATTYFDFKR---------PKG----LTMKFRDIVRRTYTPFLIGLNNPPGAVDFPAIGLEIKG 353
            .....|.|..:         |||    :.|.|..:|.|.....||.....|.|.....|..|
 Worm   662 EHIREYDDSGKQPPRVVRGSPKGDIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNE--- 723

  Fly   354 QMVHCP-------ESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVI------------- 398
              .|.|       :.|.||.:            |...:..:.......:::|
 Worm   724 --NHMPRITDDYRQENMLLEM------------CKECWDRNPDKRPTIKKLIESISTVYPLSKGN 774

  Fly   399 LVGEQARAQDGLRRRMDKIKNSIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYP 463
            ||.:..|..:   :..|:::..:....:.:...:.:.:.||:.:.||.||:.|..|..:..::|.
 Worm   775 LVDQMIRMSE---KYADELEQMVAIRTADLADAQMQTMRLLNEMLPASIAKDLKNGLIMPPRSYE 836

  Fly   464 DVTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGL-HRAS 527
            ..|::|..|..|.::..|::|..||:.|..:|..||......|.|||||.|:.|.||||: |...
 Worm   837 SATVMFVQICDFNALMKRSSPEQVIAFLNDIYDQFDTVIKRHDAYKVETTGETYMVASGVPHENE 901

  Fly   528 IYDAHKVAWMALKMIDACSKHI-THD-GEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIAN 590
            .....:||.::|::.:....:: .|| ..::::|||.|.|.:.|||:|.:.|||||||.:|..|:
 Worm   902 GRHIFEVAEISLEIREISYIYVLQHDKNYKLRIRIGFHAGPIAAGVIGIRSPRYCLFGDTVNFAS 966

  Fly   591 KFESGSEALKINVSPTTKD---------------------------WLTKHEGFEFELQPRDPSF 628
            :.:|.....:|..|..|..                           ||.:|  ...|.:|..|..
 Worm   967 RMQSNCPPNQIQTSEITARLLFDSHEYKFVKRGIVHVKGKGEVNCYWLNEH--LHEETEPPLPPM 1029

  Fly   629 LPKEFPNP 636
            .|  .|||
 Worm  1030 TP--VPNP 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	<109..208	CDD:462233	15/115 (13%)
		HNOBA	259..451	CDD:462234	43/246 (17%)
		Guanylate_cyc	457..647	CDD:425528	63/210 (30%)
odr-1	NP_001362115.1	Periplasmic_Binding_Protein_type1	63..378	CDD:471960
		PK_GC	495..768	CDD:270894	51/330 (15%)
		CYCc	803..996	CDD:214485	61/192 (32%)