DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gycalpha99B and Gucy2d

DIOPT Version :9

Sequence 1:NP_477088.2 Gene:Gycalpha99B / 43493 FlyBaseID:FBgn0013972 Length:676 Species:Drosophila melanogaster
Sequence 2:NP_001124165.1 Gene:Gucy2d / 14918 MGIID:106030 Length:1117 Species:Mus musculus


Alignment Length:286 Identity:104/286 - (36%)
Similarity:156/286 - (54%) Gaps:25/286 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   401 GEQARAQDGLRRRMDKIKNSIE----EANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKT 461
            |::....|.:.|.::|...|:|    |....:..||:|...||..:.|..:|..|.:|::::.:.
Mouse   818 GKKTSVVDSMLRMLEKYSESLEDLVQERTEELELERRKTERLLSQMLPPSVAHALKMGTTVEPEY 882

  Fly   462 YPDVTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGL-HR 525
            :..|||.||||||||:|.:.:.|..|:..|..||..||...|..||||||||||||.||||| .|
Mouse   883 FDQVTIYFSDIVGFTTISALSEPIEVVGFLNDLYTLFDAVLDSHDVYKVETIGDAYMVASGLPRR 947

  Fly   526 ASIYDAHKVAWMALKMID-ACSKHITHDGE-QIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTI 588
            .....|.::|.:||.::. |.:..:.|..: .|::|.|||:|..:|||||..||||||||.:|..
Mouse   948 NGNRHAAEIANLALDILSYAGNFRMRHAPDVPIRVRAGLHSGPCVAGVVGLTMPRYCLFGDTVNT 1012

  Fly   589 ANKFESGSEALKINVSPTT-KDWLTKHEGFEFELQPRDPSFLPKEFPNPGGTETCYFLE---SFR 649
            |::.||.....:|:||.:| :..|:..||::.:::.:      .|....|..|| |:|.   .|.
Mouse  1013 ASRMESTGLPYRIHVSQSTVQALLSLDEGYKIDVRGQ------TELKGKGLEET-YWLTGKVGFC 1070

  Fly   650 NPALDSEL------PLVEHINVSMKT 669
            .| |.:.|      |..:.||..::|
Mouse  1071 RP-LPTPLSIKPGDPWQDRINQEIRT 1095

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gycalpha99BNP_477088.2 HNOB 76..208 CDD:285002
HNOBA 259..451 CDD:285003 14/53 (26%)
CYCc 430..619 CDD:214485 83/192 (43%)
Guanylate_cyc 457..647 CDD:278633 80/196 (41%)
Gucy2dNP_001124165.1 PBP1_sensory_GC_DEF-like 71..445 CDD:380594
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 529..557
PK_GC-2D 554..818 CDD:270945 104/286 (36%)
CYCc 855..1044 CDD:214485 81/188 (43%)
Interaction with NCALD. /evidence=ECO:0000250|UniProtKB:P51839 874..915 16/40 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1096..1117 104/286 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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