Protein Alignment Gycalpha99B and ADCY5

DIOPT Version :9

• Sequence 1: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001365188.1
• Gene: ADCY5 / 111
• HGNCID: 236
• Length: 1286
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 72/276 - (26%)
• Similarity: 134/276 - (48%)
• Gaps: 35/276 - (12%)

  Fly   385 ISDIPLHDATREVILVGEQARAQDGLRRRMDKIKNSIEEANSAVTKERKKNVSLLHLIFPAEIAE 449
            :|::.:...| .::.|.....|:...|:...:.:..| :|.....:|.::...||..:.|..:|
Human   380 VSNVLIFSCT-NIVGVCTHYPAEVSQRQAFQETRECI-QARLHSQRENQQQERLLLSVLPRHVA- 441

  Fly   450 KLWLGSSIDAK------------TYPDVTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFC 502
             :.:.:.|:||            .:.:|:|||:||.||||:.|:.|...::..|..|:..||:..
Human   442 -MEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLA 505

  Fly   503 DFFDVYKVETIGDAYCVASGLHRASIYDAHKVAWMALKMIDACS--KHITHDGEQIKMRIGLHTG 565
            ......:::.:||.|...|||..|....||....|.:.||:|.|  :.:|  |..:.||:|:|:|
Human   506 AENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVT--GVNVNMRVGIHSG 568

  Fly   566 TVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINVSPTTKDWLTKHEGFEFELQPRDPSFLP 630
            .|..||:|.:..::.::.:.||:||..|:|.:|.:|:::..|.::|..    ::|::
Human   569 RVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNG----DYEVE-------- 621

  Fly   631 KEFPNPGGTETCYFLE 646
               |..||....|..|
Human   622 ---PGCGGERNAYLKE 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002
		HNOBA	259..451	CDD:285003	12/65 (18%)
		CYCc	430..619	CDD:214485	59/202 (29%)
		Guanylate_cyc	457..647	CDD:278633	60/204 (29%)
ADCY5	NP_001365188.1	AC_N	1..458	CDD:318454	15/81 (19%)
		Guanylate_cyc	460..633	CDD:306677	56/189 (30%)
		DUF1053	668..760	CDD:399378
		Guanylate_cyc	1087..1281	CDD:306677

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810