DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gycalpha99B and LOC100496629

DIOPT Version :9

Sequence 1:	NP_477088.2	Gene:	Gycalpha99B / 43493	FlyBaseID:	FBgn0013972	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_031761324.1	Gene:	LOC100496629 / 100496629	-ID:	-	Length:	744	Species:	Xenopus tropicalis

Alignment Length:	333	Identity:	109/333 - (32%)
Similarity:	169/333 - (50%)	Gaps:	61/333 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 GLDGLTCNGLFISDI-------------PLHDATREV--------------------ILVGEQAR 405
            |...:.||....:|:             .|.|.::|:                    :||
Frog   316 GQTSMLCNPALTTDLNYVQECLHKNANKKLRDKSKEILSTISLKISLFTVACFMYPLVLV----- 375

  Fly   406 AQDGLRRRMDKIKN---SIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTI 467
               ..::..:.|:|   :::|....:.|||:....|||.:.|..:|::|.....::|::|..|||
Frog   376 ---SFKQMTEWIQNYAINLKERTEDLKKERRLAEDLLHQMLPKSVAKQLRKHKHVEAESYEQVTI 437

  Fly   468 LFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAH 532
            .||||||||.|.:..||..|:.||..||..||...:.::|||||||||||.|.|||...: |:.|
Frog   438 FFSDIVGFTLISASCTPLQVVEMLNSLYVCFDSRIESYNVYKVETIGDAYMVVSGLPERN-YNKH 501

  Fly   533 --KVAWMALKMIDACSK----HITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANK 591
              ::|.|:|.::.|..:    |:.:  |::::|.|:|||..:|||||.|||||||||.:|..|::
Frog   502 ADEIAKMSLDLVAAVRQVIIPHLPN--ERLQLRAGIHTGPCVAGVVGYKMPRYCLFGDTVNTASR 564

  Fly   592 FESGSEALKINVSPTTKDWLTKHEGFEFELQPRDPSFLPKEFPNPGGTETCYFLESFRNPALDSE 656
            .||.|...||::|..|...|...:.:|.||:..      .|....|..:| |:|...:|.::.::
Frog   565 MESTSLPQKIHISSATYQVLLVDDAYEIELRGE------IEVKGKGKMKT-YWLLGNKNYSVQND 622

  Fly   657 LPLVEHIN 664
             .||.|.|
Frog   623 -SLVCHWN 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002
		HNOBA	259..451	CDD:285003	20/112 (18%)
		CYCc	430..619	CDD:214485	84/194 (43%)
		Guanylate_cyc	457..647	CDD:278633	83/195 (43%)
LOC100496629	XP_031761324.1	HNOBA	<391..421	CDD:400168	9/29 (31%)
LOC100496629	XP_031761324.1	Guanylate_cyc	427..613	CDD:306677	83/195 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010