DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7582 and tmem86a

DIOPT Version :9

Sequence 1:	NP_651710.1	Gene:	CG7582 / 43492	FlyBaseID:	FBgn0039681	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001013530.1	Gene:	tmem86a / 541385	ZFINID:	ZDB-GENE-050320-81	Length:	237	Species:	Danio rerio

Alignment Length:	238	Identity:	88/238 - (36%)
Similarity:	123/238 - (51%)	Gaps:	26/238 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KSQGPKLVPFLVTIVLYFSLVRKDPQGELWTTVLKCLPIFALVFYVVAKGISLKKEYRRSLWILL 73
            ||:|||||||.....:||.|.........::.::||||||.|..:::|.||:....:..:..||.
Zfish     9 KSEGPKLVPFFKATCVYFVLWLPTSSPSWFSALIKCLPIFCLWVFLLAHGINFLGAHSSARKILA 73

  Fly    74 GLVFSSGGDALL---NINLFPFGMISFGVAHVFYISAFGWKPIKWFIGLLLYVAVSLCKFTGHYI 135
            ||:||:.|||.|   ....|..|::.|.:.|:.|.||||.||:....||::.| :|...:|..|
Zfish    74 GLIFSALGDAFLIWQEQGYFSHGLLMFAITHILYSSAFGMKPLNSRAGLIIAV-ISGFSYTLLY- 136

  Fly   136 RIPYLEYLKPPVVYFVHTKLDEILIIGVPIYCFLITTMLWRSLAR---AVDSRNFLAVFCAIGAI 197
                 .||..|..|.            |.:|..||..|.||::|.   |.|...:..:...:||:
Zfish   137 -----PYLSGPFTYL------------VAVYIALIGFMGWRAIAGVQFANDLWTWTKLSACLGAV 184

  Fly   198 LFVISDALIAVTMFVGVPLPCARLQIMITYYAAQFAIALSTAD 240
            ||::||..|||..|. .|:|.:|..||.||||||..||||..:
Zfish   185 LFMVSDLTIAVNKFC-FPVPHSRAIIMATYYAAQMLIALSAVE 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7582	NP_651710.1	YhhN	38..237	CDD:285222	74/204 (36%)
tmem86a	NP_001013530.1	YhhN	37..224	CDD:285222	75/206 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580944
Domainoid	1	1.000	108	1.000	Domainoid score	I6378
eggNOG	1	0.900	-	-		E1_KOG4804
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41679
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4647
OMA	1	1.010	-	-		QHG48600
OrthoDB	1	1.010	-	-		D1516092at2759
OrthoFinder	1	1.000	-	-		FOG0003055
OrthoInspector	1	1.000	-	-		otm25443
orthoMCL	1	0.900	-	-		OOG6_106299
Panther	1	1.100	-	-	LDO	PTHR31885
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5328
SonicParanoid	1	1.000	-	-		X3969
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800