DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bub3 and AT1G69400

DIOPT Version :9

Sequence 1:	NP_001287587.1	Gene:	Bub3 / 43490	FlyBaseID:	FBgn0025457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_564965.1	Gene:	AT1G69400 / 843272	AraportID:	AT1G69400	Length:	314	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	98/320 - (30%)
Similarity:	157/320 - (49%)	Gaps:	18/320 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRPPEFKLNNPPEDLISAVKFGPKSNQYMAASSWDGTLRFYDVPANQLRQKFVQDAPLLDCAF-M 64
            |.....:..||.||.:|.::|.|:||..:.| |||..||.|||.::.|..:....|.||||.| .
plant     1 MSGDRLEFENPIEDAVSRLRFSPQSNNLLVA-SWDSYLRLYDVESSSLSLELNSQAALLDCCFEN 64

  Fly    65 DIVHVVSGSLDNQLRLFDVNTQAESIIGAHEEPIRCVEHAEYVNGILTGSWDNTVKLWDMREKRC 129
            :.....||| |..:|.:|:|......||.|::....:.::.....:::..:|..:|.||.|::..
plant    65 ESTSFTSGS-DGFIRRYDLNAGTVDTIGRHDDISTSIVYSYEKGEVISTGFDEKIKFWDTRQRES 128

  Fly   130 VGTFEQNNGKVYSMSVIDEKIVVATSDRKVLIWDLRKMDSYIMKRESSLKYQTRCIRLFPNKEGY 194
            :.......|.|..::|....:||.. |..:.|:|||.:|.......|.::...|||...|...||
plant   129 LVFSTDAGGAVGCVTVSGNNLVVCV-DASMHIYDLRNLDEAFQSYASQVEVPIRCITSVPYSRGY 192

  Fly   195 VMSSIEGRVAVEYLDHDPEV---QRRKFAFKCH-RNREQNIEQIYPVNALSFHNVYQ-TFATGGS 254
            .:.|::|||||::    |..   ...|::|:|| ::|...::.:. :||:.|..... ||.||.:
plant   193 AVGSVDGRVAVDF----PNTSCSSEIKYSFRCHPKSRNGRLDGVC-INAIEFSPCGSGTFVTGDN 252

  Fly   255 DGIVNIWDGFNKKRLCQFHEYDTSISTLNFSSDGSALAIGCS--YLD--QLPETPATVPH 310
            :|.|..|:..:::||.:...|..||::|.|...|..|||..|  |.|  :..|.|....|
plant   253 EGYVISWNAKSRRRLNELPRYSNSIASLAFDHTGELLAIASSHTYQDAKEKEEAPQVFIH 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bub3	NP_001287587.1	WD40	<10..296	CDD:225201	91/291 (31%)
		WD40	16..262	CDD:295369	75/251 (30%)
		WD40 repeat	16..53	CDD:293791	15/36 (42%)
		WD40 repeat	59..93	CDD:293791	12/34 (35%)
		WD40 repeat	98..134	CDD:293791	5/35 (14%)
		WD40 repeat	141..175	CDD:293791	9/33 (27%)
		WD40 repeat	182..222	CDD:293791	14/42 (33%)
		WD40 repeat	237..283	CDD:293791	15/46 (33%)
AT1G69400	NP_564965.1	WD40	13..294	CDD:421866	89/288 (31%)
		WD40 repeat	16..53	CDD:293791	15/37 (41%)
		WD40 repeat	58..92	CDD:293791	12/34 (35%)
		WD40 repeat	97..132	CDD:293791	5/34 (15%)
		WD40 repeat	140..173	CDD:293791	9/33 (27%)
		WD40 repeat	180..219	CDD:293791	14/42 (33%)
		WD40 repeat	234..261	CDD:293791	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1036
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1048963at2759
OrthoFinder	1	1.000	-	-		FOG0003514
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102928
Panther	1	1.100	-	-	O	PTHR10971
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.780