DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk19 and ppk18

DIOPT Version :9

Sequence 1:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_609308.3	Gene:	ppk18 / 34295	FlyBaseID:	FBgn0265001	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	543	Identity:	123/543 - (22%)
Similarity:	213/543 - (39%)	Gaps:	110/543 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FREKLCNSFAHSNIHGMQ-HVFGEQHLWQRCLWLAIVLGAVITGFSLYTVLMHRHSEQLLVSLIE 92
            |||.|..|:    |:|:. .::.....:.:.:|||.     :|...:||.::  .::.:|..|::
  Fly    13 FREFLRQSY----INGLHPFLYHTPVRYAKAIWLAF-----LTAIMIYTHIV--IADLILEYLVQ 66

  Fly    93 TTQL----PVYHI---DFPAVAVCPWNHFNWQRAPSAFIRFLPRHPNAELRET------------ 138
            .|::    .:.|:   .||||.||..|..|.:...|...:......|:.|:..
  Fly    67 PTEIHMAPDLVHVANSPFPAVGVCTSNKINGRLLRSYAEKLFHHQGNSSLQAVALDLDDMANRLL 131

  Fly   139 ------FRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDE 197
                  ...|.:..:..|.:..:|:..|......|..| .:.|::..::..|.:| |....||.
  Fly   132 VLAQFYLNPLESDHERWNATELDRLHRLLVAYHNGAGY-SVRDILRDLSPGCGDL-VIRGIVFG- 193

  Fly   198 TPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFMN 262
            .|.:..:||::..|....|.:||       .::...:||...:.....|...:...:..|.|.:|
  Fly   194 LPVNASQLFLKRPTSSNVCCIFN-------YRRPSYSQFLTKRAEEDSEMRAVPMVVFESNSILN 251

  Fly   263 NI----------DALTPFGMN----LMIKEPRQWS-------NEMMYHLYPDTENFVAVHPLVTE 306
            ::          |....|..|    |:|.....::       .|::...|...|  :.:.|:...
  Fly   252 SVQFVLQDTPKEDITNTFHSNSAFQLIIFPQEDYATIQSTTLGEVLVDHYSIVE--IPIQPMFFS 314

  Fly   307 TSPNTYEMSPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDG-- 369
            :......:.|..||||:.:| .....|.|. |:.:.||:||....:...|.|    ..||:.|
  Fly   315 SGDGVRGVPPHIRRCYYPEE-GMRLLNQSY-YSLDECLLVCRMKSMIDHCGC----VSPPLTGSS 373

  Fly   370 --VPECGINDAQCLGNNSDI------FTYVKMGDQEKYINDSRQGHFCD-CPDNCNSRLYEMSLN 425
              :..|.:.|..||.....|      |.|:: ..:|..:  .||   |: |...||.....::.|
  Fly   374 MDLDYCMLPDLPCLMRWKSIWYGYSDFAYLQ-NKEENLV--QRQ---CEHCLPTCNGVSMSITTN 432

  Fly   426 VRKLDYPKNSTDQ---LIKAQVYYGQRVMTKIITKLKYTN----------IDLLANFGGIISLYI 477
            |..|....||:..   |:|.........:.|:..||::..          :.||..||||:||..
  Fly   433 VAPLRRTYNSSGYFTGLLKGLTNERPLAIIKLFFKLRFAQATKSQMVSSWVVLLNRFGGILSLMY 497

  Fly   478 GASVMSFIELLFVL-GKLMWGFI 499
            |.|::|:||:|:.| ||   ||:
  Fly   498 GFSIVSYIEILYYLTGK---GFV 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	112/520 (22%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079	3/40 (8%)
ppk18	NP_609308.3	ASC	16..510	CDD:279230	115/528 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020