Protein Alignment ppk19 and Asic3

DIOPT Version :10

• Sequence 1: NP_651708.2
• Gene: ppk19 / 43489
• FlyBaseID: FBgn0039679
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_038963092.1
• Gene: Asic3 / 286920
• RGDID: 708578
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 110/537 - (20%)
• Similarity: 186/537 - (34%)
• Gaps: 139/537 - (25%)

  Fly    12 RPRPGLLRF-RNNPRGIKFREKLCNSFAHSNIHGMQHVFGEQHL-WQRCLWLAIVLGAVIT---- 70
            :||.||... |.....|:.....|      .:||:.|:||...| .:|.||...||.::..
  Rat     2 KPRSGLEEAQRRQASDIRVFASSC------TMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQ 60

  Fly    71 ---------GFSLYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVC-----------PWNHFN 115
                     .|...|.|..|.|.||               .||||.:|           | |..:
  Rat    61 VAERVRYYGEFHHKTTLDERESHQL---------------TFPAVTLCNINPLRRSRLTP-NDLH 109

  Fly   116 WQRAPSAFIRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFM 180
            |  |.:|.:...|....|.|| ...|..|....|....|:..::..:   .|.|   :.|::...
  Rat   110 W--AGTALLGLDPAEHAAYLR-ALGQPPAPPGFMPSPTFDMAQLYAR---AGHS---LEDMLLDC 165

  Fly   181 TYRCDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAG 245
            .||      ...|    .|.:...:|.|    .|||..|||    .:....|:.      ....|
  Rat   166 RYR------GQPC----GPENFTVIFTR----MGQCYTFNS----GAHGAELLT------TPKGG 206

  Fly   246 EDSGLKFTINASYS----FMNNIDALTPFGMNLMIK-----EPRQWSNEMMYHLYPDTENFVAVH 301
            ..:||:..::....    ...:::. |||.:.:.::     ||.. .:::.:...|..:.||:..
  Rat   207 AGNGLEIMLDVQQEEYLPIWKDMEE-TPFEVGIRVQIHSQDEPPA-IDQLGFGAAPGHQTFVSCQ 269

  Fly   302 PLVTETSP------NTYEMSPKKRRCYFDDEKNPTF----QNTSLTYNRENCLVVCLHLVVWKTC 356
            .......|      ||..:.|..    ||.|.:...    ...|..|:...|.:.|....|.:.|
  Rat   270 QQQLSFLPPPWGDCNTASLDPDD----FDPEPSDPLGSPRPRPSPPYSLIGCRLACESRYVARKC 330

  Fly   357 QCSLPAFLPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKYINDSR-QGHFCDCPDNCNSRLY 420
            .|.: ..:|                 .||.:.:..:..|......|:. :...|.||:.|.:..|
  Rat   331 GCRM-MHMP-----------------GNSPVCSPQQYKDCASPALDAMLRKDTCVCPNPCATTRY 377

  Fly   421 EMSLNVRKL-----------DYPKNS---TDQLIKAQVYYGQRVMTKIITKLKYTNIDLLANFGG 471
            ...|::.::           .|.::.   |:.::...:::.......:..|..|...:||.:.||
  Rat   378 AKELSMVRIPSRASARYLARKYNRSESYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGG 442

  Fly   472 IISLYIGASVMSFIELL 488
            .:.|:||||:::.:|:|
  Rat   443 QMGLFIGASLLTILEIL 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	37..489	CDD:459966	103/511 (20%)
Asic3	XP_038963092.1	ENaC	17..547	CDD:273304	105/522 (20%)