Protein Alignment ppk19 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_651708.2
• Gene: ppk19 / 43489
• FlyBaseID: FBgn0039679
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 620
• Identity: 122/620 - (19%)
• Similarity: 207/620 - (33%)
• Gaps: 198/620 - (31%)

  Fly    17 LLRFRNNPRGIKFREKLCNSFAHSNIHGMQHVFGEQH------LWQRCLWLAIVLGAVITGFSL- 74
            |:.|..:.|  :..:..||   ::.|||...:...:|      .| ..|||. ..|.:...|:|
  Rat    74 LIEFHRSYR--ELFQFFCN---NTTIHGAIRLVCSKHNRMKTAFW-AVLWLC-TFGMMYWQFALL 131

  Fly    75 ------YTVLM--HRHSEQLLVSLIETTQLPVYHIDFPAVAVCPWNHFNW--------------- 116
                  |.|.:  :.:|::|:               ||||.||..|.:.:
  Rat   132 FEEYLSYPVSLNINLNSDKLV---------------FPAVTVCTLNPYRYTEIKEELEELDRITE 181

  Fly   117 --------------------QRAPSAFIRFLPRHPNAELR------------------------- 136
                                :|:....:...| ||...||
  Rat   182 QTLFDLYKYNSSYTRQAGARRRSSRDLLGAFP-HPLQRLRTPPPPYSGRTARSGSSSVRDNNPQV 245

  Fly   137 -----------------ETFRQLLAS-MD-IMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTY 182
                             :.|.|..:| :| :..:..|:.|.||::.:.|..: |:...|.||:.
  Rat   246 DRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLSDTSPA-LEEEALGNFIF- 308

  Fly   183 RCDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGED 247
                     :|.|::.|.:..........:.|.|..||...:.|....           |..|.:
  Rat   309 ---------TCRFNQAPCNQANYSKFHHPMYGNCYTFNDKNNSNLWMS-----------SMPGVN 353

  Fly   248 SGLKFTINASYS-FMNNIDALTPFGMNLMI---KEPRQWSNEMMYHLYPDTENFVAVHPLVTETS 308
            :||..|:....: |:..:..:|  |..:|:   .|| .:.::..::|.|..|..:::.....::.
  Rat   354 NGLSLTLRTEQNDFIPLLSTVT--GARVMVHGQDEP-AFMDDGGFNLRPGVETSISMRKEALDSL 415

  Fly   309 PNTYEMSPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPEC 373
            ...|      ..|..:....|........|.::.|:..|....:.|.|.|:. .|.|...||..|
  Rat   416 GGNY------GDCTENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAY-IFYPKPKGVEFC 473

  Fly   374 GINDAQCLGNNSDIFTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPK-NSTD 437
            ........|     :.|.|:  |..:..|| .|.|..|...|:...|::|....:  :|. .|.|
  Rat   474 DYRKQSSWG-----YCYYKL--QGAFSLDS-LGCFSKCRKPCSVINYKLSAGYSR--WPSVKSQD 528

  Fly   438 ---QLIKAQVYY-------GQRVMTKIITKLKY---------TNIDLLANFGGIISLYIGASVMS 483
               :::..|..|       |...:.....:|.|         |.:.||:|.|...||:.|:||:|
  Rat   529 WIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLS 593

  Fly   484 FIEL------LFVLGKLM---------WGFIRDAR 503
            .:|:      |.|:..||         |...|.||
  Rat   594 VVEMAELIFDLLVITLLMLLRRFRSRYWSPGRGAR 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	109/573 (19%)
		AceK	116..>139	CDD:295079	6/99 (6%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	120/614 (20%)
		deg-1	88..600	CDD:273309	111/574 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820