Protein Alignment ppk19 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_651708.2
• Gene: ppk19 / 43489
• FlyBaseID: FBgn0039679
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 131/614 - (21%)
• Similarity: 216/614 - (35%)
• Gaps: 195/614 - (31%)

  Fly    17 LLRFRNNPRGIKFREKL---CNSFAHSNIHGMQHVFGEQHLWQRCLW--LAIVLGAVIT---GFS 73
            |.|.:..| |..::|.|   ||   ::|.||.:.:..|... ::.:|  |.::...::.   |..
  Rat    11 LHRLQKGP-GYTYKELLVWYCN---NTNTHGPKRIICEGPK-KKAMWFLLTLLFACLVCWQWGVF 70

  Fly    74 LYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVC---PW------------------------ 111
            :.|.|    |.::.|||    .:....::||||.||   |:
  Rat    71 IQTYL----SWEVSVSL----SMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLYKLMEAVLDKIL 127

  Fly   112 ----NHFN---------WQRAPSAFI-RFLPRHP---------------------NAE-LRETFR 140
                :|.|         |...|...| ...|.||                     ||: .:...|
  Rat   128 APKSSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMR 192

  Fly   141 QLLASMDIMNFSNFNRIR-------ILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDET 198
            ...|:..:..|.||....       ||...|:  .|.:...||:. |.|..|.:.:|  |:|...
  Rat   193 LCSANGTVCTFRNFTSATQAVTEWYILQATNI--FSQVLPQDLVG-MGYAPDRIILA--CLFGTE 252

  Fly   199 PYDCCK------LFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINAS 257
            |   |.      :|..:.   |.|.:||..::|.:...           :..|.:.|||..::..
  Rat   253 P---CSHRNFTPIFYPDY---GNCYIFNWGMTEKALPS-----------ANPGTEFGLKLILDIG 300

  Fly   258 YSFMNNIDALTPF-----GMNLMIKEPRQW---SNEMMYHLYPDTENFVAVHPLVTETSPNTYEM 314
            .      :...||     |..||:.|.|.:   ..|.:|.: ..||..:.|  |:.:........
  Rat   301 Q------EDYVPFLASTAGARLMLHEQRTYPFIREEGIYAM-AGTETSIGV--LLDKLQGKGEPY 356

  Fly   315 SPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTC-------QCSLPAFLPPIDGVPE 372
            ||    |..:. .:...||....||....:..|||     :|       .||...:|.|:..
  Rat   357 SP----CTMNG-SDVAIQNLYSDYNTTYSIQACLH-----SCFQDHMIHNCSCGHYLYPLPA--- 408

  Fly   373 CGINDAQCLGNNSDI--FTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPKNS 435
               .:..|  ||.|.  :.|..:..|...:  .|:.....|.::||...|:|::::  .|:|..:
  Rat   409 ---GEKYC--NNRDFPDWAYCYLSLQMSVV--QRETCLSMCKESCNDTQYKMTISM--ADWPSEA 464

  Fly   436 TDQ----------------------LIKAQVYYGQRVMTKIITKLKYTNID-LLANFGGIISLYI 477
            ::.                      ::|..:|: |....:.|.:....||. ||:|.||....::
  Rat   465 SEDWILHVLSQERDQSSNITLSRKGIVKLNIYF-QEFNYRTIEESPANNIVWLLSNLGGQFGFWM 528

  Fly   478 GASVMSFIELLFVLGKLMWGFIRDARIKL 506
            |.||:..||    .|:::..||....|||
  Rat   529 GGSVLCLIE----FGEIIIDFIWITVIKL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	117/570 (21%)
		AceK	116..>139	CDD:295079	8/45 (18%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	127/603 (21%)
		deg-1	29..538	CDD:273309	119/578 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820