DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk19 and egas-2

DIOPT Version :9

Sequence 1:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_507640.2	Gene:	egas-2 / 190561	WormBaseID:	WBGene00013487	Length:	919	Species:	Caenorhabditis elegans

Alignment Length:	345	Identity:	67/345 - (19%)
Similarity:	129/345 - (37%)	Gaps:	74/345 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 DLMNFMTYRCDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPH 239
            ||.|::.:....|.:.:.            ::.....|.|.|..||..           :|.:.:
Worm   623 DLFNWIAFEDQRLDLEND------------IYKWNDVVLGNCFTFNHQ-----------DQNFTY 664

  Fly   240 KLSTAGEDSGLKFTINASYSFM-NNIDALTPF----GMNLMI--KEPRQWSNEMMYHLYPDTENF 297
            .:...|...|::       :|| ...|...|:    ||.:.|  :|...:|..:.|:..|:.::.
Worm   665 LMRRPGRHGGIQ-------AFMKTRQDEYAPWYDTAGMLVFIHNREDYVFSESVRYNAQPNAQST 722

  Fly   298 VAVHPLVTETSPNTYEMSPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPA 362
            :.:...........|....||.    .:.||..:..   .|..:.||..|....:.:.|||..|.
Worm   723 INIFMTRYTRLGGRYGKCVKKP----SEVKNYYYPG---AYTTDGCLRTCYQDRMQQECQCMDPR 780

  Fly   363 FLPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMS---L 424
            : |.......|.:::..|:...||     ..||...:.:       |.||..|:::.|.::   .
Worm   781 Y-PKAPNATSCQLSERSCVTEASD-----AAGDPSTWSS-------CVCPLPCSNQEYSVTWSKA 832

  Fly   425 NVRKLDYPKNSTDQLIKAQVYYGQRVMTKII-TKLKY------TNID---LLANFGGIISLYIGA 479
            |...:......:..:...|..|..::|..|: .||.:      ..:|   .|:..||.:.:.:|.
Worm   833 NFVNMPITCEKSSDVATCQANYVDQLMVSIVLPKLDFQIYAETPAMDFNKFLSQLGGQLGVLMGI 897

  Fly   480 SVMSFIELLFVLGKLMWGFI 499
            ::::|||::|    ||:|.:
Worm   898 NLVTFIEVVF----LMFGVL 913

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	63/333 (19%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079
egas-2	NP_507640.2	ASC	<650..908	CDD:279230	59/299 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820