DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk19 and egas-3

DIOPT Version :9

Sequence 1:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_507638.2	Gene:	egas-3 / 190557	WormBaseID:	WBGene00013480	Length:	921	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	56/303 - (18%)
Similarity:	110/303 - (36%)	Gaps:	66/303 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 VKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFM-NNIDALTPF----G 271
            |.|.|..||..           ::.:.:.:...|...|::       :|| ...|...|:    .
Worm   647 VLGNCFTFNHR-----------DRNFTYLMRRPGRHGGIQ-------AFMKTRQDEYAPWYDTAA 693

  Fly   272 MNLMI--KEPRQWSNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKRRCYFDDEKNPTFQNT 334
            :|:.|  ::...:|..:.|:..|:.::.:.:...........|....||.    .:.||..:..
Worm   694 INVFIHNRDDYVFSESVRYNAQPNAQSTINIFMTRYTRLGGNYGKCIKKP----SEVKNYYYPG- 753

  Fly   335 SLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKY 399
              .|..:.||..|....:.:.|.|..|.: |.......|.:::..|:...|:     ..||...:
Worm   754 --AYTTDGCLRTCYQDRMKEECNCMDPRY-PQAPNSTSCQLSERSCVTEASE-----AAGDPSTW 810

  Fly   400 INDSRQGHFCDCPDNCNSRLYEMS---LNVRKLDYPKNSTDQLIKAQVYYGQRVMTKIITKLKYT 461
            .:       |.||..|:::.|.::   .|...|......:..:...|..|..::|..||    ..
Worm   811 SS-------CVCPLPCSNQEYSVTWSKANFVNLPITCEKSSDVATCQKQYKDQLMVSII----LP 864

  Fly   462 NID--------------LLANFGGIISLYIGASVMSFIELLFV 490
            .:|              .|:..||.:.:.:|.:|::|||::|:
Worm   865 QLDFKIYAETPAMDFNKFLSQLGGQLGVLMGINVVTFIEVVFL 907

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	55/300 (18%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079
egas-3	NP_507638.2	ASC	<649..907	CDD:279230	54/299 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820