Protein Alignment ppk19 and asic-2

DIOPT Version :10

• Sequence 1: NP_651708.2
• Gene: ppk19 / 43489
• FlyBaseID: FBgn0039679
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 110/569 - (19%)
• Similarity: 186/569 - (32%)
• Gaps: 172/569 - (30%)

  Fly    40 SNIHGMQHVFGEQHLWQRCLWLAI---VLGAVITGFSLYTVLMHRHSEQLLVSLIETTQLPVYHI 101
            |.:..:.||....:...|..|:||   |||  :..:.||.::....|....|:    |::.....
 Worm    17 STVAVVPHVANANNKISRIFWIAIFLFVLG--MFAYELYILIAKFFSYPATVN----TEILFEKQ 75

  Fly   102 DFPAVAVCPWNHFNWQ--RAPSAFIRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIR------ 158
            .||.|.||..|.:.:.  ::.|||             .:...|:.:........|:..:
 Worm    76 IFPVVTVCNMNPYKYSVVKSNSAF-------------SSVNTLMTTYSDATVGTFSTDKWGLYAD 127

  Fly   159 --------------ILTKRNLTG--------ISYLKMTDLMNFMTYRCDELFVADSCVFDETPYD 201
                          ::.:.||..        .:|..:....:|....|.|   :|...|.:..|
 Worm   128 NDETYDLDSRAADALVLEANLISDTAKVPALYTYADLIQDCSFAGIPCSE---SDFTKFIDPVY- 188

  Fly   202 CCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFMN-NID 265
                        |.|..||...|.|            :.:|..|...|||..:..:.:..| |.|
 Worm   189 ------------GACYSFNEDASLN------------YSVSREGIQFGLKLMLTVTQTKTNGNTD 229

  Fly   266 AL-------TPFGMNLMIKEPRQWSNEMMYHL-YPD------TENFVAVHPLVT--ETSPNTYEM 314
            :|       ...|:|.....|...||.:...: |..      |:|..|..|..|  :..|::.:
 Worm   230 SLPTTKLAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLTQNVRAKKPYGTCVDREPDSSD- 293

  Fly   315 SPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQ 379
                   |:.|          ..|..|.|...|........|||:.|..        ..|..|..
 Worm   294 -------YYKD----------FIYTLETCFNGCKQRDTIAKCQCANPRL--------ALGSTDTA 333

  Fly   380 CLGNNSDIFTYVKM-GDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPK---------- 433
            |....:|:.....: |:|.....:......|:|...|:...|..::::.:  :|.
 Worm   334 CQPIKADLDCLQTLKGNQTSSTPNIDLLVECNCNPPCDESTYTPTVSLAQ--FPSTSYYVATSST 396

  Fly   434 ------NSTDQLIKA----QVYYGQRVMT----------KIITKLK-YTNIDLLANFGGIISLYI 477
                  :||:....:    |.:|....|.          ::.|:.. ||..:::.:.||...|::
 Worm   397 AGVGSCSSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNVINDLGGQAGLWL 461

  Fly   478 GASVMSFIE---LLFVLGK--LMWGFIR----------DARIKLKEYTK 511
            |.||:|.:|   |:.|:|.  :..|.|:          |.|||..|..|
 Worm   462 GLSVISVVEMTGLMLVMGAFCVTGGAIKMAPDDDEIENDHRIKDVEDVK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	37..489	CDD:459966	100/533 (19%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	99/531 (19%)