DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk19 and egas-1

DIOPT Version :9

Sequence 1:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001359624.1	Gene:	egas-1 / 180219	WormBaseID:	WBGene00013486	Length:	922	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	70/369 - (18%)
Similarity:	144/369 - (39%)	Gaps:	80/369 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 NLTGISYL--------KMTDLMNFMT------------YRCDELFVADSCVFDETPYDCCK-LFV 207
            :||.||.|        ::.|::.|:|            :...:||  :...|::...|..: :..
Worm   580 DLTMISLLNDLMQNPSQIKDMVPFITGLLTDSERSDLSWDAGDLF--NWIAFEDQRLDLNRDIHK 642

  Fly   208 REQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFM-NNIDALTPF- 270
            ....|.|.|..||..           ::.:.::|.::|...|::       :|| ...|...|:
Worm   643 WNDVVLGNCFTFNHR-----------DRNFTYRLRSSGRHGGIQ-------AFMKTRQDEYAPWY 689

  Fly   271 ---GMNLMI--KEPRQWSNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKRRCYFDDEKNPT 330
               .:|:.|  ::...:|..:.|:..|:.::.:.:...........|....||.    .:.||..
Worm   690 DTAAINVFIHNRDDYVFSESVRYNAQPNAQSTMNIFMTRYTRLGGRYGKCVKKP----SEVKNYY 750

  Fly   331 FQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGNNSDIFTYVKMGD 395
            :..   .|..:.||..|....:.:.|.|..|.:......|..|.:::..|:...|:     ..||
Worm   751 YPG---AYTTDGCLRTCYQDRMKQECNCMDPRYPQAPGNVTSCQLSERSCVTVASE-----AAGD 807

  Fly   396 QEKYINDSRQGHFCDCPDNCNSRLYEMS---LNVRKLDYPKNSTDQLIKAQVYYGQRVMTKIIT- 456
            ..|:.:       |.||..|:::.|.::   .|...|......:..:...:.:|..::|..|:.
Worm   808 PSKWWD-------CVCPLPCSNQEYSVTWSKANFVNLPIICGKSSDVSTCKAHYIDQLMVSIVLP 865

  Fly   457 ----KLKYTN--ID---LLANFGGIISLYIGASVMSFIELLFVL 491
                |:...|  :|   .|:..||.:.:.:|.::::|||::|:|
Worm   866 QLDFKIYAENPAMDFNKFLSQLGGQLGVLMGINLVTFIEVVFLL 909

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	68/365 (19%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079
egas-1	NP_001359624.1	deg-1	<595..908	CDD:273309	63/351 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810