DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk19 and del-10

DIOPT Version :9

Sequence 1:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_495302.3	Gene:	del-10 / 174069	WormBaseID:	WBGene00020897	Length:	1069	Species:	Caenorhabditis elegans

Alignment Length:	460	Identity:	95/460 - (20%)
Similarity:	157/460 - (34%)	Gaps:	137/460 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 EKLCNSFAHSNIHGMQHVFGEQHLWQRCLWLAIVLGAVITGFSLYTVLMHRHSE-QLLVSLIETT 94
            ::..::|..:|:..:.|:.....: .|.||..|::..||      .||:..:|: :|.:|....|
Worm    69 KQFLDAFKDANMDAVHHLNAASPV-TRGLWCMIIIAFVI------LVLVQCYSQIKLYISEPVAT 126

  Fly    95 QLPVYH---IDFPAVAVCPWNHFNWQRAPSAFIRFLPRHPNA----------ELRETFRQLLASM 146
            .:...:   |.||.||:|..|.|........  |.:.|...:          ::...|..:|...
Worm   127 NIEAEYPSKISFPTVAICNNNQFRLTYLTGG--RIMNRRSKSISGSLLSTGHDVESVFDTVLRKS 189

  Fly   147 DIMNFSNFNRIRILTK-RNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCCKL--FVR 208
            ..|:...|.|.....| |.:.|.::...|.                           |||  |..
Worm   190 WDMDAVKFLRSAAHWKSRMILGCTWPNGTS---------------------------CKLSDFKA 227

  Fly   209 EQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINA-SYSFMNNIDALTPF-- 270
            ..|..|.|...|:            :...|::::.:||..||:..:|. ||   ..:||.|..
Worm   228 VWTTTGLCWAINT------------DPHNPYEVTGSGEGHGLRLLLNVESY---ERVDACTKHFR 277

  Fly   271 -----GMNLMIKEPRQWSNEMMYHLYPDTE-NFVAVHPLVTETSPNTYEMS-PKKRR-------- 320
                 |:.::|.....         .||:. |.|.|        |:.|.|. |.|.:
Worm   278 TKTLPGLKILIYNQTD---------IPDSSMNGVNV--------PSGYSMDIPFKMQHRSKLTGV 325

  Fly   321 -CYFDDEKNPTFQNTSLTYNR-ENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGN 383
             |.   |:|......|..:|. ||...            |:|..::..::....|.:..|. ..|
Worm   326 HCI---EENDEQIEASTDFNNPENIRT------------CTLRRYMTEVENSCHCTLRRAY-TSN 374

  Fly   384 NSDIFTYVKM---------GDQEKYINDSR-QGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTDQ 438
            ::|    |||         |..:|.:...| :|....|...|.|..|....::.:|  |:|....
Worm   375 STD----VKMKACNVDQYFGCAQKAMQRIREEGTASTCLPPCKSIDYTAWQDMNRL--PQNLMPA 433

  Fly   439 LIKAQ 443
            ||:.|
Worm   434 LIEEQ 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	94/452 (21%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079	2/32 (6%)
del-10	NP_495302.3	ASC	83..>419	CDD:279230	87/423 (21%)
del-10	NP_495302.3	ASC	<789..849	CDD:279230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820