Protein Alignment ppk19 and Asic3

DIOPT Version :9

• Sequence 1: NP_651708.2
• Gene: ppk19 / 43489
• FlyBaseID: FBgn0039679
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 555
• Identity: 114/555 - (20%)
• Similarity: 197/555 - (35%)
• Gaps: 159/555 - (28%)

  Fly    24 PRGIKFREKLCNS----FAHS-NIHGMQHVFGEQHL-WQRCLWLAIVLGAVIT------------ 70
            |.|::..::...|    ||:| .:||:.|:||...| .:|.||...||.::..
Mouse     4 PSGLEEAQRRQASDIRVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYY 68

  Fly    71 -GFSLYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVC-----------PWNHFNWQRAPSAF 123
             .|...|.|..|.|.||               .||||.:|           | |..:|  |.:|.
Mouse    69 GEFHHKTTLDERESHQL---------------TFPAVTLCNINPLRRSRLTP-NDLHW--AGTAL 115

  Fly   124 IRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELF 188
            :...|....|.|| ...|..|....|....|:..::..:   .|.|   :.|::....||
Mouse   116 LGLDPAEHAAYLR-ALGQPPAPPGFMPSPTFDMAQLYAR---AGHS---LEDMLLDCRYR----- 168

  Fly   189 VADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFT 253
             ...|    .|.:...:|.|    .|||..|||    .::...|:.      ....|..:||:..
Mouse   169 -GQPC----GPENFTVIFTR----MGQCYTFNS----GAQGAELLT------TPKGGAGNGLEIM 214

  Fly   254 INASYS----FMNNIDALTPFGMNLMI-----KEPRQWSNEMMYHLYPDTENFVAVHPLVTETSP 309
            ::....    ...:::. |||.:.:.:     :||.. .:::.:...|..:.||:.........|
Mouse   215 LDVQQEEYLPIWKDMEE-TPFEVGIRVQIHGQEEPPA-IDQLGFGAAPGHQTFVSCQQQQLSFLP 277

  Fly   310 ------NTYEMSPKKRRCYFDDEKNPTF--QNTSLTYNRENCLVVCLHLVVWKTC---------- 356
                  ||..:.|.     ||.|.:...  .::|..|:...|.:.|....|.:.|
Mouse   278 PPWGDCNTASVDPD-----FDPEPSDPLGSPSSSPPYSLIGCRLACESRYVARKCGCRMMHMPGN 337

  Fly   357 ----------QCSLPAF-------LPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKYINDSR 404
                      .|:.||.       ||    ||.....|...||   .:..::.:...:..:....
Mouse   338 SPVCSPQQYKDCASPALGKAHLFSLP----VPIHSDIDHNPLG---QVLLFLALRPADAMLRKDT 395

  Fly   405 QGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTDQLI-----KAQVYYGQRVMT-----------K 453
                |.||:.|.:..|...|::.::  |..::.:.:     :::.|..:.|:.           .
Mouse   396 ----CVCPNPCATTRYAKELSMVRI--PSRASARYLARKYNRSETYITENVLVLDIFFEALNYEA 454

  Fly   454 IITKLKYTNIDLLANFGGIISLYIGASVMSFIELL 488
            :..|..|...:||.:.||.:.|:||||:::.:|:|
Mouse   455 VEQKAAYEVSELLGDIGGQMGLFIGASLLTILEIL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	109/536 (20%)
		AceK	116..>139	CDD:295079	7/22 (32%)
Asic3	XP_006535700.1	ASC	21..546	CDD:383197	111/538 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920