Protein Alignment ppk19 and Asic2

DIOPT Version :9

• Sequence 1: NP_651708.2
• Gene: ppk19 / 43489
• FlyBaseID: FBgn0039679
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 598
• Identity: 125/598 - (20%)
• Similarity: 202/598 - (33%)
• Gaps: 215/598 - (35%)

  Fly    15 PGLLRFRNNPRGIKFREKLCNSFAHSNIHGMQHV----------FGEQHLWQRCLWLAIVLGAVI 69
            ||:.| |..|           |.:.:.:||::|:          |..:.||  .|.....||.::
Mouse    51 PGVAR-RGRP-----------SLSRTKLHGLRHMCAGRTAAGGSFQRRALW--VLAFCTSLGLLL 101

  Fly    70 TGFS---LYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVCPWNHFNWQRAPSAFIRFLPRH- 130
            :..|   ||.:....|:.   |....:.|||     ||||.||..|...:.|.....: :...|
Mouse   102 SWSSNRLLYWLSFPSHTR---VHREWSRQLP-----FPAVTVCNNNPLRFPRLSKGDL-YYAGHW 157

  Fly   131 -----PNAELRETFRQLLASMD--------IMNFSNFNRIRILTKRNLTGISYL-------KMTD 175
                 ||...|....:||...:        :.:|..|     |..|:..|||..       ::.|
Mouse   158 LGLLLPNRTARPLVSELLRGDEPRRQWFRKLADFRLF-----LPPRHFEGISAAFMDRLGHQLED 217

  Fly   176 LMNFMTYRCDEL-----FVADSC------------------------------VFDETPYDCCKL 205
            ::....|| .||     |.:.||                              ||  |.|
Mouse   218 MLLSCKYR-GELCGPHNFSSVSCPPREPALSDPALPRSPEALRWAPGTGHQAPVF--TKY----- 274

  Fly   206 FVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLST--AGEDSGLKFTINASYSFMNNIDALT 268
                    |:|.:|||  .|:.:.          .|:|  .|..:||:..::...      |...
Mouse   275 --------GKCYMFNS--GEDGKP----------LLTTVKGGTGNGLEIMLDIQQ------DEYL 313

  Fly   269 PF-----------GMNLMI---KEPRQWSNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKR 319
            |.           |:.:.|   .|| .:..|:.:.:.|..:.|||     |:....|| :.|...
Mouse   314 PIWGETEETTFEAGVKVQIHSQSEP-PFIQELGFGVAPGFQTFVA-----TQEQRLTY-LPPPWG 371

  Fly   320 RCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSL------PAFLPPIDGVPECGINDA 378
            .|...:.....|...|:|    .|.:.|....:.:.|.|.:      ..|..| :...||.   .
Mouse   372 ECRSSEMGLDFFPVYSIT----ACRIDCETRYIVENCNCRMVHMPGDAPFCTP-EQHKECA---E 428

  Fly   379 QCLGNNSDIFTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTDQLI--- 440
            ..||                 :...:..::|.|...||...|...|::.|:  |..::.:.:
Mouse   429 PALG-----------------LLAEKDSNYCLCRTPCNLTRYNKELSMVKI--PSKTSAKYLEKK 474

  Fly   441 --KAQVYYGQRVMTKII--TKLKYTNID---------LLANFGGIISLYIGASVMSFIE------ 486
              |::.|..:.::...|  ..|.|..|:         ||.:.||.:.|:||||:::.:|
Mouse   475 FNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIY 539

  Fly   487 ------LLFVLGK 493
                  ||.:|||
Mouse   540 ELIKEKLLDLLGK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	39..489	CDD:279230	115/568 (20%)
		AceK	116..>139	CDD:295079	5/28 (18%)
Asic2	XP_006532059.1	ASC	64..590	CDD:383197	119/573 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920