Protein Alignment ppk19 and asic1

DIOPT Version :10

• Sequence 1: NP_651708.2
• Gene: ppk19 / 43489
• FlyBaseID: FBgn0039679
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_004912018.1
• Gene: asic1 / 100489966
• XenbaseID: XB-GENE-977699
• Length: 525
• Species: Xenopus tropicalis
• Alignment Length: 505
• Identity: 104/505 - (20%)
• Similarity: 188/505 - (37%)
• Gaps: 135/505 - (26%)

  Fly    40 SNIHGMQHVFG-EQHLWQRCLWLAIVLGAVITGFSLYTVLMHRHSEQLL-------VSLIETTQL 96
            |.:||:.|:|. |:...:|.:|:...||::       ::|::..:|:::       |:.::....
 Frog    24 STLHGLAHIFTYERFSCRRLIWVLCFLGSL-------SLLLYVCTERIIYYFEYPHVTKLDEIST 81

  Fly    97 PVYHIDFPAVAVCPWNHFNWQRA-------PSAFIRFLPRH---PNAELR-ETFRQLLASMDIMN 150
            |  .:.||||..|..|.|.:.|.       ....:..|...   |:::|. |...::|  .|..|
 Frog    82 P--RMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEIL--QDKAN 142

  Fly   151 FSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCCKLFVREQTVKGQ 215
            |.|| :.:....|.....:...:.:::....||.:|..|.|              ||...|..|:
 Frog   143 FRNF-KPKPFNMREFYDRTGHDIREMLLSCKYRGEECSVDD--------------FVPVFTRYGK 192

  Fly   216 CLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFMNNIDALTPF---------- 270
            |..|||  ..|.|.        |...:..|..:||:..::...      |...|.
 Frog   193 CYTFNS--GRNGRS--------PLVTTKGGTGNGLELMLDIQQ------DEYLPVWGETDETSFE 241

  Fly   271 -GMNLMI---KEPRQWSNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKRRC--------YF 323
             |:.:.|   .|| .:.:::.:.:.|..:.||:     .:....|| :.|....|        :|
 Frog   242 AGIKVQIHSQDEP-PFIDQLGFGVAPGFQTFVS-----CQEQRLTY-LPPPWGDCKSSAMDSEFF 299

  Fly   324 DDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGNNSDIF 388
            |            ||:...|.:.|....:.:.|.|.: ..:|.         :.|.|...
 Frog   300 D------------TYSISACRIDCETRYLVENCNCRM-VHMPG---------DAAYCTPE----- 337

  Fly   389 TYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTDQLI-----KAQVYYGQ 448
            .|.:..|........:...||.|...||...|...|::.|:  |..::.:.:     |::.|..:
 Frog   338 LYKECADPALDFLVEKDNDFCVCETPCNMTRYGKELSMVKI--PSKASARYLAKKYNKSEQYIAE 400

  Fly   449 RVMTKII--TKLKYTNID---------LLANFGGIISLYIGASVMSFIEL 487
            .::...|  ..|.|..|:         ||.:.||.:.|:||||:::.:||
 Frog   401 NILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTVLEL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk19	NP_651708.2	ASC	37..489	CDD:459966	104/505 (21%)
asic1	XP_004912018.1	ENaC	18..507	CDD:273304	104/505 (21%)