Protein Alignment ppk30 and scnn1b

DIOPT Version :10

• Sequence 1: NP_651706.1
• Gene: ppk30 / 43487
• FlyBaseID: FBgn0039677
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 588
• Identity: 123/588 - (20%)
• Similarity: 191/588 - (32%)
• Gaps: 224/588 - (38%)

  Fly    14 DNDDDHKESKKKLKKEGAGGWASTRRYARIPLK-IMAALATVY----------VSILSSERYFYY 67
            ||.:.|  ..|::.|||             |.| :|..:.|:.          |.||:   |..|
 Frog    37 DNTNTH--GPKRIIKEG-------------PKKRVMWFILTLVFAGLVFWQWGVLILT---YLSY 83

  Fly    68 WVQTSIERTDMHVSEIDFPAVTIIPIN-------------LSILKAEKLSK--------AYNLVQ 111
            .|..|:   .:....::|||||:...|             |..|.|..|.:        |....|
 Frog    84 GVSVSL---SIGFKTMEFPAVTVCNANPYKYSRVKPLLKDLDALVATALDRIQFSSQDQANTFTQ 145

  Fly   112 S----------VVW-------------QTPMSARLTDEN--------FTEFSELENWNAQSWGIY 145
            |          .:|             ..|:...:.|.|        |...||.:...:|.:.:.
 Frog   146 SSTNQNVTLDPTLWNHIPLVVIDETDPSNPIVNNIFDNNAIYSKNNSFRNSSEDQTSYSQRYKVA 210

  Fly   146 QALQMNCQHFFTECQWRR-----KAMNCCDLFRPTKTFN----------GFAFE-------FNSL 188
            ..|   |.:..|:|.:|.     :|:....|.:.:..|:          ||..|       |...
 Frog   211 MKL---CTNNNTQCVYRNFTSGIQALQEWYLLQLSSIFSNVPLADRIAMGFKAEDLILTCLFGGQ 272

  Fly   189 VSSGRDET--------------W------PWSVASCGSYSGLNVKIKRQQGLY-----TLNTMGV 228
            ..|.|:.|              |      |.:.|:.|:..||.:.:..:||.|     |.....:
 Frog   273 PCSYRNFTRIYDADYGNCYIFNWGQEGEDPMASANPGADFGLKLVLDIEQGEYLPYVQTTAAARL 337

  Fly   229 IVHEPTQL-----LGMSIDYSSEDRIVVPVEPL-HFTA---ELDVRARPVQMRRCYFENEIPTGK 284
            |:|:....     ||:.....:|..|.|.|:.| |..|   ...|....:.::..|  .|..:..
 Frog   338 ILHQQRSFPFVKDLGIYAMPGTETSIAVLVDQLEHMEAPYSSCTVNGSDIPVQNLY--AEFNSSY 400

  Fly   285 SRSECIYKCHVNYIISKCNCS-LELPVKATQDEDNIAAAKESNGRRIC-------------GVKD 335
            |...|:..|:...::..|.|: .:.|:              .||...|             |::|
 Frog   401 SIQSCLRSCYQEQMVQTCGCADYQYPL--------------PNGSEYCSNDKYPDWVPCYYGLRD 451

  Fly   336 LACFNQHRLSLFSMSNIIEESRDNVFSTVDCGCFPQCGHTQY-------------------HTST 381
            .....:..:||                     |...|..|||                   |..:
 Frog   452 SVADRESCISL---------------------CQQPCNDTQYKMVISMADWPSAGAQDWIFHVLS 495

  Fly   382 YTEKMSAH---TNLAAAIEIDVYFQEETLFSYRSMLR---FTLIDLMVSYGGIAGLIMGISVLGC 440
            | ||.|:|   .|....:.:::||||   |:|||:..   ..::.|:.:.||..|..||.||| |
 Frog   496 Y-EKDSSHNITVNRNGIVRLNIYFQE---FNYRSITESEATNVVWLLSNLGGQFGFWMGGSVL-C 555

  Fly   441 INE 443
            |.|
 Frog   556 IIE 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk30	NP_651706.1	ASC	47..446	CDD:459966	114/554 (21%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	123/588 (21%)