Protein Alignment ppk30 and SCNN1A

DIOPT Version :9

• Sequence 1: NP_001263076.1
• Gene: ppk30 / 43487
• FlyBaseID: FBgn0039677
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001153048.1
• Gene: SCNN1A / 6337
• HGNCID: 10599
• Length: 728
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 61/343 - (17%)
• Similarity: 117/343 - (34%)
• Gaps: 107/343 - (31%)

  Fly   154 HFFTECQWRRKAMNCCDLFRPTKTFNGFAFEFNSLVSSGRDETWPWSVASCGSYSGLNVKIKRQQ 218
            :|...|::.:.:.|..:.........|..:.||...:|..     |..:..|..:||::.::.:|
Human   336 NFIFACRFNQVSCNQANYSHFHHPMYGNCYTFNDKNNSNL-----WMSSMPGINNGLSLMLRAEQ 395

  Fly   219 G-----LYTLNTMGVIVH---EPTQL----------LGMSIDYSSE--DRI------------VV 251
            .     |.|:....|:||   ||..:          :..||....|  ||:            .|
Human   396 NDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKETLDRLGGDYGDCTKNGSDV 460

  Fly   252 PVEPLHFTAELDVRARPVQMRRCYFENEIPTGKSRSECIYKCHVNYIISKCNCSLELPVKATQDE 316
            |||.|:                       |:..::..||:.|....:|.:|.|:. :.....|:.
Human   461 PVENLY-----------------------PSKYTQQVCIHSCFQESMIKECGCAY-IFYPRPQNV 501

  Fly   317 DNIAAAKESNGRRICGVKDLACFNQHRLSLFSMSNIIEESRDNVFSTVDCGCFPQC--------- 372
            :.....|.|:..        .|:.:.::.               ||:...|||.:|
Human   502 EYCDYRKHSSWG--------YCYYKLQVD---------------FSSDHLGCFTKCRKPCSVTSY 543

  Fly   373 ----GHTQYHTSTYTE----KMSAHTNLA------AAIEIDVYFQEETLFSYRSMLRFTLIDLMV 423
                |::::.:.|..|    .:|...|..      ...:::::|:|....:.......|::.|:.
Human   544 QLSAGYSRWPSVTSQEWVFQMLSRQNNYTVNNKRNGVAKVNIFFKELNYKTNSESPSVTMVTLLS 608

  Fly   424 SYGGIAGLIMGISVLGCI 441
            :.|....|..|.|||..:
Human   609 NLGSQWSLWFGSSVLSVV 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk30	NP_001263076.1	ASC	47..446	CDD:279230	61/343 (18%)
SCNN1A	NP_001153048.1	ENaC	113..706	CDD:273304	61/343 (18%)
		deg-1	121..631	CDD:273309	61/343 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820