DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk30 and ppk19

DIOPT Version :9

Sequence 1:	NP_001263076.1	Gene:	ppk30 / 43487	FlyBaseID:	FBgn0039677	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	107/478 - (22%)
Similarity:	169/478 - (35%)	Gaps:	132/478 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 IMAALAT---VYVSILSSERYFYYWVQTSIERTDMHVSEIDFPAVTIIPINLSILKAEKLSKAYN 108
            ::.|:.|   :|..::  .|:....:.:.||.|.:.|..||||||.:.|.|           .:|
  Fly    64 VLGAVITGFSLYTVLM--HRHSEQLLVSLIETTQLPVYHIDFPAVAVCPWN-----------HFN 115

  Fly   109 LVQSVVWQTPMSA------------------------------------RLTDENFTEFSELENW 137
                  ||...||                                    .||..|.|..|.|:..
  Fly   116 ------WQRAPSAFIRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMT 174

  Fly   138 NAQSWGIYQALQMNCQHFFT--ECQWRRKAMNCCDLFRPTKTFNGFAFEFNSLVSSGR------D 194
            :..::..|:     |...|.  .|.:.....:||.||...:|..|....|||::|...      :
  Fly   175 DLMNFMTYR-----CDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLIN 234

  Fly   195 ETWPWSVASCGSYSGLNVKIKRQQGLYTLNT---------------MGVIVHEPTQLLG-MSIDY 243
            :.:|..:::.|..|||.         :|:|.               |.:::.||.|... |....
  Fly   235 QFYPHKLSTAGEDSGLK---------FTINASYSFMNNIDALTPFGMNLMIKEPRQWSNEMMYHL 290

  Fly   244 SSEDRIVVPVEPLHFTAELDVRARPVQMRRCYFENE-IPTGK------SRSECIYKCHVNYIISK 301
            ..:....|.|.||......:......:.|||||::| .||.:      :|..|:..|....:...
  Fly   291 YPDTENFVAVHPLVTETSPNTYEMSPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKT 355

  Fly   302 CNCSLEL---PVKATQDEDNIAAAKESNGRRICGVKDLACFNQHR-----LSLFSMSNIIEESRD 358
            |.|||..   |:....:               ||:.|..|...:.     :.:......|.:||.
  Fly   356 CQCSLPAFLPPIDGVPE---------------CGINDAQCLGNNSDIFTYVKMGDQEKYINDSRQ 405

  Fly   359 NVFSTVDCGCFPQCGHTQYHTSTYTEKMSAHTNLA-AAIEIDVYFQEETLFSYRSMLRFTLIDLM 422
            ..|    |.|...|....|..|....|:....|.. ..|:..||:.:..:....:.|::|.|||:
  Fly   406 GHF----CDCPDNCNSRLYEMSLNVRKLDYPKNSTDQLIKAQVYYGQRVMTKIITKLKYTNIDLL 466

  Fly   423 VSYGGIAGLIMGISVLGCINELL 445
            .::|||..|.:|.||:..| |||
  Fly   467 ANFGGIISLYIGASVMSFI-ELL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk30	NP_001263076.1	ASC	47..446	CDD:279230	107/478 (22%)
ppk19	NP_651708.2	ASC	39..489	CDD:279230	107/478 (22%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079	4/22 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	1	1.000	-	-		FOG0009975
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920