Protein Alignment ppk30 and Asic3

DIOPT Version :10

• Sequence 1: NP_651706.1
• Gene: ppk30 / 43487
• FlyBaseID: FBgn0039677
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: XP_038963092.1
• Gene: Asic3 / 286920
• RGDID: 708578
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 98/489 - (20%)
• Similarity: 162/489 - (33%)
• Gaps: 128/489 - (26%)

  Fly    30 GAGG-------WASTRRYARIPLKIMAALATVYVSILSSERYF-YYWVQTSIERTDMHVSEIDFP 86
            |.||       ||:.         ::.:||.....:....||: .:..:|:::..:.|  ::.||
  Rat    35 GPGGLTLRRGLWATA---------VLLSLAAFLYQVAERVRYYGEFHHKTTLDERESH--QLTFP 88

  Fly    87 AVTIIPIN----------------LSILKAEKLSKAYNLVQSVVWQTPMSARLTDENFTEFSELE 135
            |||:..||                .::|..:....|..|  ..:.|.|...........:.::|
  Rat    89 AVTLCNINPLRRSRLTPNDLHWAGTALLGLDPAEHAAYL--RALGQPPAPPGFMPSPTFDMAQL- 150

  Fly   136 NWNAQSWGIYQALQMNCQHFFTECQWRRKAMNCC--DLFRPTKTFNGFAFEFNSLVSSGRDETWP 198
                     |.....:.:....:|::|.:.   |  :.|....|..|..:.|||........|.|
  Rat   151 ---------YARAGHSLEDMLLDCRYRGQP---CGPENFTVIFTRMGQCYTFNSGAHGAELLTTP 203

  Fly   199 WSVASCGSYSGLNVKIKRQQGLY---------TLNTMGVIVH-----EPTQL--LGMSIDYSSED 247
                ..|:.:||.:.:..||..|         |...:|:.|.     ||..:  ||.......:.
  Rat   204 ----KGGAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHSQDEPPAIDQLGFGAAPGHQT 264

  Fly   248 RIVVPVEPLHF---------TAELDVRARPVQMRRCYFENE--IPTGKSRSE---------CIYK 292
            .:....:.|.|         ||.||    |..     |:.|  .|.|..|..         |...
  Rat   265 FVSCQQQQLSFLPPPWGDCNTASLD----PDD-----FDPEPSDPLGSPRPRPSPPYSLIGCRLA 320

  Fly   293 CHVNYIISKCNCSL-----ELPVKATQD-EDNIAAAKESNGRRICGVKDLACFNQHRLSLFSMSN 351
            |...|:..||.|.:     ..||.:.|. :|..:.|.::..|:...|....|.........||..
  Rat   321 CESRYVARKCGCRMMHMPGNSPVCSPQQYKDCASPALDAMLRKDTCVCPNPCATTRYAKELSMVR 385

  Fly   352 IIEESRDNVFSTVDCGCFPQCGHTQYHTSTYTEKMSAHTNLAAAIEIDVYFQEETLFSYRSMLRF 416
            |                 |.....:|....|....|..|.  ..:.:|::|:.....:......:
  Rat   386 I-----------------PSRASARYLARKYNRSESYITE--NVLVLDIFFEALNYEAVEQKAAY 431

  Fly   417 TLIDLMVSYGGIAGLIMGISVLGCINELLDRFAC 450
            .:.:|:...||..||.:|.|:| .|.|:|| :.|
  Rat   432 EVSELLGDIGGQMGLFIGASLL-TILEILD-YLC 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk30	NP_651706.1	ASC	47..446	CDD:459966	90/459 (20%)
Asic3	XP_038963092.1	ENaC	17..547	CDD:273304	98/489 (20%)