Protein Alignment ppk30 and Asic2

DIOPT Version :10

• Sequence 1: NP_651706.1
• Gene: ppk30 / 43487
• FlyBaseID: FBgn0039677
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 105/498 - (21%)
• Similarity: 168/498 - (33%)
• Gaps: 123/498 - (24%)

  Fly    20 KESKKKLKKEG-----AGGWASTRRYARIPLKIMAALATVYVSILSSERYFYYWVQTSIERTDMH 79
            :.|..:.|..|     ||..|:...:.|..|.::|...::.:.:..|.....||:... ..|.:|
  Rat    58 RPSLSRTKLHGLRHMCAGRTAAGGSFQRRALWVLAFCTSLGLLLSWSSNRLLYWLSFP-SHTRVH 121

  Fly    80 ---VSEIDFPAVTIIPINLSILKAEKLSKAYNLVQSVVW---------QTPMSARLT--DE---- 126
               ..::.|||||:  .|.:.|:..:|||. :|..:..|         ..|:.:.|.  ||
  Rat   122 REWSRQLPFPAVTV--CNNNPLRFPRLSKG-DLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQ 183

  Fly   127 ------NFTEFSELENWNAQSWGIYQALQMNCQHFFTECQWRRKAM---NCCDLFRPTKTFNGFA 182
                  :|..|....::...|......|....:.....|::|.:..   |...:|    |..|..
  Rat   184 WFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVF----TKYGKC 244

  Fly   183 FEFNSLVSSGRDETWPWSVASCGSYSGLNVKIKRQQGLYTLNTMGVIVHEPTQLLGMSIDYSSED 247
            :.||    ||.|.....:....|:.:||.:.:..||..| |...|. ..|.|...|:.:...|:.
  Rat   245 YMFN----SGEDGKPLLTTVKGGTGNGLEIMLDIQQDEY-LPIWGE-TEETTFEAGVKVQIHSQS 303

  Fly   248 RIVVPVEPLHFTAELDVRARP--------VQMRRCYFENEIPTGKSRSE--------------CI 290
                  || .|..||.....|        .:.|..|...  |.|:.||.              |.
  Rat   304 ------EP-PFIQELGFGVAPGFQTFVATQEQRLTYLPP--PWGECRSSEMGLDFFPVYSITACR 359

  Fly   291 YKCHVNYIISKCNCSL-ELPVKATQDEDNIAAAKESNGRRICGVKDLACFNQHRLSLFSMSNIIE 354
            ..|...||:..|||.: .:|                      |........||:........::.
  Rat   360 IDCETRYIVENCNCRMVHMP----------------------GDAPFCTPEQHKECAEPALGLLA 402

  Fly   355 ESRDNVFSTVDCGCFPQCGHTQYHTSTYTEKMSAHTNLAAAIE----------------IDVYFQ 403
            |...|.     |.|...|..|:|:......|:.:.|: |..:|                :|::|:
  Rat   403 EKDSNY-----CLCRTPCNLTRYNKELSMVKIPSKTS-AKYLEKKFNKSEKYISENILVLDIFFE 461

  Fly   404 EETLFSYRSMLRFTLIDLMVSYGGIAGLIMGISVLGCINELLD 446
            .....:......:.:..|:...||..||.:|.|:| .|.||.|
  Rat   462 ALNYETIEQKKAYEVAALLGDIGGQMGLFIGASLL-TILELFD 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk30	NP_651706.1	ASC	47..446	CDD:459966	96/464 (21%)
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	104/492 (21%)