Protein Alignment ppk30 and Asic3

DIOPT Version :10

• Sequence 1: NP_651706.1
• Gene: ppk30 / 43487
• FlyBaseID: FBgn0039677
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 525
• Identity: 101/525 - (19%)
• Similarity: 167/525 - (31%)
• Gaps: 170/525 - (32%)

  Fly    30 GAGG-------WASTRRYARIPLKIMAALATVYVSILSSERYF-YYWVQTSIERTDMHVSEIDFP 86
            |.||       ||:.         ::.:||.....:....||: .:..:|:::..:.|  ::.||
Mouse    35 GPGGLTLRRGLWATA---------VLLSLAAFLYQVAERVRYYGEFHHKTTLDERESH--QLTFP 88

  Fly    87 AVTIIPIN----------------LSILKAEKLSKAYNLVQSVVWQTPMSARLTDENFTEFSELE 135
            |||:..||                .::|..:....|..|  ..:.|.|...........:.::|
Mouse    89 AVTLCNINPLRRSRLTPNDLHWAGTALLGLDPAEHAAYL--RALGQPPAPPGFMPSPTFDMAQL- 150

  Fly   136 NWNAQSWGIYQALQMNCQHFFTECQWRRKAMNCC--DLFRPTKTFNGFAFEFNSLVSSGRDETWP 198
                     |.....:.:....:|::|.:.   |  :.|....|..|..:.|||........|.|
Mouse   151 ---------YARAGHSLEDMLLDCRYRGQP---CGPENFTVIFTRMGQCYTFNSGAQGAELLTTP 203

  Fly   199 WSVASCGSYSGLNVKIKRQQGLY---------TLNTMGVIV-----HEPTQL--LGMSIDYSSED 247
                ..|:.:||.:.:..||..|         |...:|:.|     .||..:  ||.......:.
Mouse   204 ----KGGAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHGQEEPPAIDQLGFGAAPGHQT 264

  Fly   248 RIVVPVEPLHF---------TAELDVRARPVQMRRCYFENEIPTGKSRSE-------CIYKCHVN 296
            .:....:.|.|         ||.:|....|        |...|.|...|.       |...|...
Mouse   265 FVSCQQQQLSFLPPPWGDCNTASVDPDFDP--------EPSDPLGSPSSSPPYSLIGCRLACESR 321

  Fly   297 YIISKCNCSL-----ELPVKATQDEDNIAAAKESNGRRICGVKDLACFNQHRLSLFSMSNIIEES 356
            |:..||.|.:     ..||.:.|.                 .||.|.....:..|||:...|...
Mouse   322 YVARKCGCRMMHMPGNSPVCSPQQ-----------------YKDCASPALGKAHLFSLPVPIHSD 369

  Fly   357 RDN-------VFSTV----------DCGCFPQCGHTQY-----------------------HTST 381
            .|:       :|..:          .|.|...|..|:|                       .:.|
Mouse   370 IDHNPLGQVLLFLALRPADAMLRKDTCVCPNPCATTRYAKELSMVRIPSRASARYLARKYNRSET 434

  Fly   382 Y-TEKMSAHTNLAAAIEIDVYFQEETLFSYRSMLRFTLIDLMVSYGGIAGLIMGISVLGCINELL 445
            | ||.:         :.:|::|:.....:......:.:.:|:...||..||.:|.|:| .|.|:|
Mouse   435 YITENV---------LVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLL-TILEIL 489

  Fly   446 DRFAC 450
            | :.|
Mouse   490 D-YLC 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk30	NP_651706.1	ASC	47..446	CDD:459966	93/495 (19%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	101/525 (19%)