Protein Alignment ppk20 and scnn1a

DIOPT Version :10

• Sequence 1: NP_651705.2
• Gene: ppk20 / 43486
• FlyBaseID: FBgn0039676
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001184124.1
• Gene: scnn1a / 395013
• XenbaseID: XB-GENE-996083
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 614
• Identity: 111/614 - (18%)
• Similarity: 207/614 - (33%)
• Gaps: 197/614 - (32%)

  Fly    31 FRSYCEKSTIHCVRYLYDSHLHNLERFVVYPLFISTFNFKLYIIIVFRIIWSMLLIISIGLSFFF 95
            |..:|..:|||....|..|..:.::                      ...|.:|.:.:.||.::.
 Frog    23 FEFFCSNTTIHGAIRLVCSRSNRMK----------------------TAFWLVLFLATFGLMYWQ 65

  Fly    96 YLLLSERFVSQKLQTVVHDPQFPVFL--------VPFPAVGICTDNRINWNKL-----EAAKEQ- 146
            :.||..::.|           :||.:        :|||||.:||.|...:..:     |..||.
 Frog    66 FGLLFGQYFS-----------YPVSINLNVNSDKLPFPAVTVCTLNPYRYKAIQNDLQELDKETQ 119

  Fly   147 ----------------FLPTNASV-----------ELVE--SFTVLVSR---------------- 166
                            ::|||..|           |||.  |.|..|||
 Frog   120 RTLYELYKYNSTGVQGWIPTNQRVRRDRPGLPHLLELVPPGSKTHRVSRSVIEEELQVKRREWNI 184

  Fly   167 ------------------------METLRFGSYLSSLAELEDDNLEAVGFVNLTELAIFMTLQCS 207
                                    .|..|| .|::.||.:.::  .|:....| |..||
 Frog   185 GFKLCNETGGDCFYQTYTSGVDAIREWYRF-HYINILARVPEE--AAIDGEQL-ENFIF------ 239

  Fly   208 DIMVPKSCLWRSSSFNCCEYFVLEKTEFGFCLVFNSEVSPRSKAIKQKEGNNFYPRHNAKAGQST 272
                  :|.:...|.....|.......:|.|..||...|.:|         |.:  .::..|...
 Frog   240 ------ACRFNEESCTKANYSHFHHAIYGNCYTFNQNRSGQS---------NLW--SSSMPGIKN 287

  Fly   273 GLNFDLILNESFRRP--DSQANNNVYVSICQAPDQLNNVVYSITQNTETYVTVRPGLTWTDNTTR 335
            ||...|...:....|  .|.|...|.|...:.|..:::..::|....||.:.::      ..|..
 Frog   288 GLTLILRTEQHDYIPLLSSVAGARVLVHGHKEPAFMDDSGFNIPPGMETSIGMK------KETVN 346

  Fly   336 SIPPERRNCLFADEQGELDANDSAKN-FGKPFQLSNCLNRCHESYLIQLCNCSLPIFFLYNHRVP 399
            .:..:..:|  :::..::|    .|| |...:....|:..|.::.:::.|.|....:       |
 Frog   347 RMGGKYSDC--SEDGSDVD----VKNLFESEYTEQVCVRSCFQAAMVERCGCGYAFY-------P 398

  Fly   400 DCNAVSLRCLARHNDIFSYDKRRDEDAL-------FSATKLGMTCSCLVDCYLLDY--------Y 449
                     |:..::...|:|.:.....       |::.|||....|...|.:.:|        :
 Frog   399 ---------LSPGDEFCDYNKHKSWGHCYYKLIIEFTSNKLGCFSKCRKPCLVSEYQLTAGYSKW 454

  Fly   450 TSTTTLPLSAHKLPKD----PHQKLFRVDVHYQVETTPLYRTSLEFTIIDLIANLGGIFGLCLGA 510
            .:..:.....|.|.:.    ....:.:::::::.......:.|....::.|::.||..:.|..|:
 Frog   455 PNRVSQDWVFHTLSRQYNLTDRNGIAKLNIYFEELNYKTIQESPTINMVMLLSLLGSQWSLWFGS 519

  Fly   511 SMVSA---FELIYYLTVGLAMHLYDHQYY 536
            |::|.   .||:..|.:.:.:.|: |:||
 Frog   520 SVLSVVEMLELVIDLVIIVLIMLF-HRYY 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk20	NP_651705.2	ASC	34..521	CDD:459966	105/594 (18%)
scnn1a	NP_001184124.1	ENaC	18..602	CDD:273304	111/614 (18%)