Protein Alignment ppk20 and asic5

DIOPT Version :10

• Sequence 1: NP_651705.2
• Gene: ppk20 / 43486
• FlyBaseID: FBgn0039676
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_017951381.2
• Gene: asic5 / 100498195
• XenbaseID: XB-GENE-983430
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 490
• Identity: 106/490 - (21%)
• Similarity: 162/490 - (33%)
• Gaps: 148/490 - (30%)

  Fly   122 VPFPAVGICTDNRINWNKLEAAKEQFLPTNASVELVESFTVLVSRMETLRFGSYLSSLAELEDDN 186
            :.|||:..|..||.....:......|...|           :||.:  |.|.|..|...|::
 Frog   455 IDFPAITFCNLNRFQTKAVNNLSIAFFLWN-----------IVSAV--LHFTSIASDPGEMQ--- 503

  Fly   187 LEAVGFVNLTE-LAIFMTLQCSDIMVPKSCLWRSSSFN--CC-EYFVLEKTEFGFCLVFNSEVSP 247
             |...|:.|.: .:|....:.....:..|.|.:.|.|.  |. |.|....||:|.|..||.....
 Frog   504 -EVTDFLKLNKNFSIKEFTKNYGFYLNNSTLLKCSFFGYPCYPEDFEHIFTEYGNCYTFNYNTVS 567

  Fly   248 RSKAIKQKEGNNFYPRHNAKAGQSTGLNFDLILNESFRRPDSQANNNVYVSICQAPDQLNNVVYS 312
            .:|.|             ..||:...:.||:
 Frog   568 MNKRI-------------TTAGRGLSVLFDI---------------------------------- 585

  Fly   313 ITQNTETYVTVRPGLTWTDN------TTRSIPPE------------------RRNCLFADEQGEL 353
                .:|..|..|.|.:.|.      .:..:||.                  ||......|....
 Frog   586 ----KQTEFTDEPSLGFVDAGISFVLHSPLVPPRFDGLGLHSPAGMHAHVSMRRFKTVIQEHPWG 646

  Fly   354 DANDSAK-NFGKPFQLSNCLNRCHESYLIQLCNCSLPIFFLYNHRVPDCNAVSL-RCLARHNDIF 416
            :.|.|.| .:.:.:....||..|...|:...|.|   |.||......:|:...| .|::|
 Frog   647 ECNPSLKLKYHEIYSTYGCLQECKSYYIQNECGC---IPFLLPGNGKECDLQQLYNCVSR----- 703

  Fly   417 SYDKRRDEDALFSATKLGMTCS-------CLVDCYLLDY--YTSTTTLP-------LSAHKLPKD 465
                     ||::..|..: ||       |.|.|...|:  ..|.:|.|       ||| ||.|.
 Frog   704 ---------ALYTIEKSEL-CSMGTYNSTCPVPCEETDFPATISYSTFPSDKAAQFLSA-KLSKS 757

  Fly   466 P---HQKLFRVDVHYQVETTPLYRTSLEFTIIDLIANLGGIFGLCLGASMVSAFELIYYLTVGLA 527
            .   ...|..:|:.|......:.:.....|..:|::|:||..||..||||::..|::.|
 Frog   758 ALYMRNNLVYIDIKYHEMNYKIMKQQKALTASELLSNIGGQLGLFCGASMITIIEVLEY------ 816

  Fly   528 MHLYDHQYYGVLFKHLKA----KWVNLKGYLRNEV 558
              |:.:.|:..:|..||.    ::.|.:...|.|:
 Frog   817 --LFTNSYWMCVFILLKTPRAPEYTNNQPRYREEI 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk20	NP_651705.2	ASC	34..521	CDD:459966	97/447 (22%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:462410
		Peptidase_C1A	158..360	CDD:239068
		ASC	387..816	CDD:459966	97/447 (22%)