Protein Alignment ppk21 and scnn1b

DIOPT Version :9

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 99/519 - (19%)
• Similarity: 189/519 - (36%)
• Gaps: 124/519 - (23%)

  Fly    65 DPKMRNYLNIRVIWLLILLTTSIGAIVVYV-DLNELY---QTVRIQTTIKNTMLPIFRIPFPSIG 125
            ||.:.|::.:    ::|..|.....||..: |.|.:|   .:.|..:..:.:....:::   ::.
 Frog   155 DPTLWNHIPL----VVIDETDPSNPIVNNIFDNNAIYSKNNSFRNSSEDQTSYSQRYKV---AMK 212

  Fly   126 LCPRNRLNWKILETEAVDHFLGANVSAAQKDLFVKFFTAAGDPHLSRLNEMSNFFGNKTLTDELH 190
            ||..|       .|:.|.....:.:.|.|:               ..|.::|:.|.|..|.|.:.
 Frog   213 LCTNN-------NTQCVYRNFTSGIQALQE---------------WYLLQLSSIFSNVPLADRIA 255

  Fly   191 MLDHLDLREVYKFIQFRCQDLFHTCRWRGNPVNCCEVIEYQFTEAGLCFVFNTEISPASRQKARE 255
            |             .|:.:||..||.:.|.|.:..........:.|.|::||.       .:..|
 Frog   256 M-------------GFKAEDLILTCLFGGQPCSYRNFTRIYDADYGNCYIFNW-------GQEGE 300

  Fly   256 DKYYPLRTPHYGEGSGLDLFLRLNRSFIRP---GKRGINVMIKQPQQW---SDVVRHVPHEAHTR 314
            |   |:.:.:.|...||.|.|.:.:....|   ......:::.|.:.:   .|:..:......|.
 Frog   301 D---PMASANPGADFGLKLVLDIEQGEYLPYVQTTAAARLILHQQRSFPFVKDLGIYAMPGTETS 362

  Fly   315 ISITPRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPDF--EYWVGNCRSRCHQEHVLNLCKC 377
            |::     :.|:......|.....:.|.::  |....:.:|  .|.:.:|...|:||.::..|.|
 Frog   363 IAV-----LVDQLEHMEAPYSSCTVNGSDI--PVQNLYAEFNSSYSIQSCLRSCYQEQMVQTCGC 420

  Fly   378 SPSIFFPISDKDNFTACKASDF----KCLYDNRFTFSIERHPEEDDFVKNPFKESMICDCFTSCS 438
            : ...:|:.:...:  |....:    .|.|..|            |.|.:  :||.|..|...|:
 Frog   421 A-DYQYPLPNGSEY--CSNDKYPDWVPCYYGLR------------DSVAD--RESCISLCQQPCN 468

  Fly   439 QLVF---------------DRVFTTTTLD----NNETDTEAGTMRLDIFYQSGWFIQYQTNMRFT 484
            ...:               |.:|...:.:    :|.|....|.:||:|::|...:.....:....
 Frog   469 DTQYKMVISMADWPSAGAQDWIFHVLSYEKDSSHNITVNRNGIVRLNIYFQEFNYRSITESEATN 533

  Fly   485 FVELLASFGGIIGLFLGASLLSAFEL-------AYYFSIGLYLYIHGKRKLRK------PEPGV 535
            .|.||::.||..|.::|.|:|...|.       .:...:.|..:|..:|:.|:      |.|.|
 Frog   534 VVWLLSNLGGQFGFWMGGSVLCIIEFGEIIIDCVWITILKLLAWIKDRRQRRQRAQYADPPPTV 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	92/489 (19%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	99/519 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I6952
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4834
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970