Protein Alignment ppk21 and Asic5

DIOPT Version :9

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_067345.1
• Gene: Asic5 / 58170
• MGIID: 1929259
• Length: 495
• Species: Mus musculus
• Alignment Length: 553
• Identity: 125/553 - (22%)
• Similarity: 198/553 - (35%)
• Gaps: 166/553 - (30%)

  Fly    37 LGKLWHFM----LP-------YLKDYAAESSVHGIRYLADPKMRNYLNIR-VIWLLILLTTSIGA 89
            |||:..::    ||       :.:|:|..:|.|||..:|    :|...:| ||||.::|.:.  :
Mouse    16 LGKIKRYLSKRPLPSPTDRKKFDQDFAMSTSFHGIHNIA----QNQNKVRKVIWLAVVLGSV--S 74

  Fly    90 IVVYVDLNELYQTVRIQTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLGANVSAAQ 154
            ::|:...:.|.......||....:..:.:|.||::.||..||     .:||||..|
Mouse    75 LLVWQIYSRLVNYFTWPTTTSIEVQYVEKIEFPAVTLCNLNR-----FQTEAVSRF--------- 125

  Fly   155 KDLFVKFFTAAGDPHLSRLNEMSNFFGNKTLTDELHMLDHLDLREVYKFIQF------------- 206
               .:.||.......:.||.|:|   .|.|.:.|  .||.:...:.:...:|
Mouse   126 ---GIIFFLWDIVSKVLRLQEIS---ANNTGSPE--TLDFVTNHQNFSITEFVKNNGFYLNNDTL 182

  Fly   207 -RCQDLFHTCRWRGNPVNCCEVIEYQFTEAGLCFVFNTEISPASRQKAREDKYYPLRTPHYGE-- 268
             .|:....||    :|.:    .::.|||.|.||.||                       |||
Mouse   183 VHCEFFGKTC----SPKD----FKHVFTEYGNCFTFN-----------------------YGENI 216

  Fly   269 ---------GSGLDLFLRLNRSFIR----PG--KRGINVMIKQPQ---QWSDVVRHVPHEAHTRI 315
                     |.||.|.|.:::....    ||  ..|:..:|..|:   |:..:....|...|.|:
Mouse   217 QNKNKVSVSGRGLKLLLDVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARV 281

  Fly   316 SITPRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPS 380
            :|....||..|..           :|:...|...:||  ..|....|...|...|:..||.|.|.
Mouse   282 TIRQLKTVHQEYP-----------WGECNPNIKLRNF--ITYSTYGCLKECKARHIQRLCGCLPF 333

  Fly   381 IFFPISDKDNFTACKASD-FKC---LYDNRFTFSIERHPEEDDFVKNPFKESMIC-------DCF 434
            :.     ..|...|...: :.|   :.|:     |||              ..:|       .|.
Mouse   334 LL-----PGNGVECDLLEYYNCVSPILDH-----IER--------------KGLCTMGTHNSSCP 374

  Fly   435 TSCSQLVFDRVFTTTT-------------LDNNETDTEAGTMRLDIFYQSGWFIQYQTNMRFTFV 486
            .||.:..:....:.:|             |:.::.......:.::|.|....:...|.....:..
Mouse   375 VSCEETEYPATVSYSTFPSQRATRFLAKKLNQSQEYIRENLVNIEINYSDLNYKITQQQKAVSVP 439

  Fly   487 ELLASFGGIIGLFLGASLLSAFELAYYFSIGLY 519
            ||||..||.:|||.||||::..|:..||....|
Mouse   440 ELLADVGGQLGLFCGASLITIIEIIEYFFTNFY 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	116/520 (22%)
Asic5	NP_067345.1	ASC	41..466	CDD:366339	116/520 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820