DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk21 and asic2

DIOPT Version :9

Sequence 1:	NP_651704.2	Gene:	ppk21 / 43485	FlyBaseID:	FBgn0039675	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	XP_005164179.1	Gene:	asic2 / 407669	ZFINID:	ZDB-GENE-040513-4	Length:	564	Species:	Danio rerio

Alignment Length:	506	Identity:	107/506 - (21%)
Similarity:	191/506 - (37%)	Gaps:	114/506 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 AESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLNELYQTVRIQTTIKNTMLPIF 117
            :.:.:||:|::..|.  |.|:.|..| :|...|.:|.::.: ..|.|...:...|..:.......
Zfish    69 SRTRLHGLRHICSPS--NSLSRRAFW-MIAFCTCLGLLLSW-SSNRLLHWLAFPTHTRVHTEWAK 129

  Fly   118 RIPFPSIGLCPRNRLN-WKILETEA--VDHFLG---ANVSAAQKDLFVKFFTAAGDPHLSRLNEM 176
            .:.||::.:|..|.:. :.:.:::.  ..|:||   ||.:|  :.|.:...........|:|::.
Zfish   130 ELAFPTVTICNNNPVRLYHLTKSDLYFAGHWLGLLLANRTA--RPLVLDLLQDDRRGWFSKLSDF 192

  Fly   177 SNFFGNKTLT-DELHMLDHLDLREVYKFIQFRCQDLFHTCRWRGNPVNCCEVIEYQ--FTEAGLC 238
            ..|...:... ..|..:|.|.         .:.:|:...|::||.|   |....:.  ||..|.|
Zfish   193 RLFLPPRRFEGTSLEFMDRLG---------HQLEDMLLACKYRGEP---CGAHNFSTVFTRYGKC 245

  Fly   239 FVFNTEISPASRQKAREDKYYPLRTP-HYGEGSGLDLFLRLNRSFIRP---------GKRGINVM 293
            ::||.         |.|.|  .|||. ..|.|:||::.|.:.:....|         .:.|:.|.
Zfish   246 YMFNA---------AEEGK--TLRTTMKGGTGNGLEIMLDIQQDEYLPVWGETEETAFEAGVRVQ 299

  Fly   294 IKQPQQWSDVVRHVPHEAHTRISITP---RFTVTDERTRT-VTPEIRRCIFGDEVDNPHYKNFPD 354
            |....:       .|........:.|   .|..|.|:..| :.|....|: ...:|:..::
Zfish   300 IHSQAE-------PPFVHELGFGVAPGFQTFVATQEQRLTYLPPPWGECV-SRALDSGLFQ---- 352

  Fly   355 FEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDKDNFTACKASDFK-----------------CL 402
             .|.|..||..|...:::..|.|. .::.|    .:...|....:|                 |:
Zfish   353 -VYSVSACRIECETRYIVENCNCR-MVYMP----GDSPYCTPEQYKDCAEPALAALSAVEGTNCI 411

  Fly   403 YDNRFTFSIERHPEEDDFVKNPFKES--MICDCFTSCSQLVFDRVFTTTTLDNNETDTEAGTMRL 465
            .  |...::.|:.:|...||.|.|.|  .:...|....:.:.|.:..                 |
Zfish   412 C--RSPCNMTRYNKELSMVKIPSKTSARYLEKKFNRSEKYITDNILV-----------------L 457

  Fly   466 DIFYQSGWFIQYQT---NMRFTFVELLASFGGIIGLFLGASLLSAFELAYY 513
            |:|:::   :.|:|   ...:....||...||.:|||:|||:|:..||..|
Zfish   458 DVFFEA---LNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTLLELFDY 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	106/504 (21%)
asic2	XP_005164179.1	ASC	71..538	CDD:295594	107/504 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020