DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk21 and Nach

DIOPT Version :9

Sequence 1:	NP_651704.2	Gene:	ppk21 / 43485	FlyBaseID:	FBgn0039675	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_001334724.1	Gene:	Nach / 36864	FlyBaseID:	FBgn0024319	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	521	Identity:	116/521 - (22%)
Similarity:	222/521 - (42%)	Gaps:	85/521 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 YLK----DYAAESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVV----YVDLNELYQTV 103
            ||:    |:.|.||:||::|..|......  :.::||||.:...|.|:|:    |:|    |::.
  Fly    22 YLRRTWSDFCATSSIHGLKYTRDEDTNKI--VHLVWLLISVVMFICAVVMARTFYMD----YRSS 80

  Fly   104 RIQTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILETEAVDHFL----GANVSAAQKDLFVKFFTA 164
            ..:..:::...|:.|:.||.:.:||....|.:  ::||..:.|    ||.:....:.|.:.:...
  Fly    81 PTRMNVESDNTPVNRLYFPPVTICPDVLFNMQ--KSEAFLNTLRLPKGAELRGILRKLHIFYGFM 143

  Fly   165 AGDPHLSR--LNEMSNFFGNKTLTDELHMLDHLDLREVYKFIQFRCQDLFHTCRWRGNPVNCCEV 227
            ..|...|.  :.:|          :.|..|::|.:.|..:.:::.|.::.:.||:.|..::|.::
  Fly   144 LDDERYSAEDIEQM----------EALLFLNNLTIPEFVEHLRWNCDEILYRCRFNGEIMDCSKI 198

  Fly   228 IEYQFTEAGLCFVFNTEISPASRQKA---------REDKYYPLRTPHY-------GEGSGLDLFL 276
            .:...|..|.|..||.      |||.         ...|.:.|.:.::       |...||.:.:
  Fly   199 FQLSKTFFGHCCSFNL------RQKGWVNNKLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVV 257

  Fly   277 RL---NRSFIRPGKRGINVMIKQPQQW---SDVVRHVPHEAHTRISITPRFTVTDERTRTVTPEI 335
            |.   |...::....|:.::|::...:   ....:.:...:.|..::.|:.|......:.:..|.
  Fly   258 RYKDDNYDPLQSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETFAAVRPQETFCSSAVKALIIEE 322

  Fly   336 RRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPI---SDKDNFTACKAS 397
            |.|:|.:|..   .:.|.|:.|  .||...|...:::..|.|. :.||..   ||:    .|...
  Fly   323 RNCVFQNEFP---MRYFSDYVY--PNCELNCRVTNMVKFCGCH-TYFFDFNRTSDR----ICTFR 377

  Fly   398 DFKCLYDN--RFTFSIERHPEEDDFVKNPF---KESMICDCFTSCSQLVFDRVFTTTTLDNNETD 457
            |..||.||  |......::.:.:..:....   |:|..|.|..:|..:.:|...|...|:.|...
  Fly   378 DIPCLVDNFGRLLLICSKYSDFNRLLSANIITRKKSTQCYCPLTCEHIDYDVQLTNFPLELNMPV 442

  Fly   458 TE---AGTMR----LDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLGASLLSAFELAYYFS 515
            .:   :|..:    |.:|..|..:.:.:.::....|.|:::.|....||:|.|:||..|:.||||
  Fly   443 ADKFYSGLAKNDGVLHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMSMLSVVEIIYYFS 507

  Fly   516 I 516
            :
  Fly   508 V 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	109/508 (21%)
Nach	NP_001334724.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4697
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020