DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk21 and ppk14

DIOPT Version :9

Sequence 1:	NP_651704.2	Gene:	ppk21 / 43485	FlyBaseID:	FBgn0039675	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_609017.2	Gene:	ppk14 / 33887	FlyBaseID:	FBgn0031803	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	125/494 - (25%)
Similarity:	224/494 - (45%)	Gaps:	57/494 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SRLGKLWHFMLPYLKDYAAESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLNEL 99
            |.:.:.|..:   :..|.:.|.:||:..|..|.||.  .:||:|.|.|:........|...|.:.
  Fly    32 SEIQRAWTLL---IDSYISRSHIHGLYLLFLPSMRR--RMRVLWALALICACTVLFHVSYLLGDR 91

  Fly   100 YQTVRIQTTIKNTMLPIFRIPFPSIGLCPRNRLNW-KILETEAVDHFLGANVSAAQKDLFVKFFT 163
            |...:.||.:.:....|..|.||.:.:|.:||||| ::.|.:::     .|::.:|.:||.:..|
  Fly    92 YHNKQFQTIVAHAHASIHHIAFPVVIICNKNRLNWSRLPEIKSL-----YNITPSQDELFDRILT 151

  Fly   164 AAGDPHLSRLNEMSNFFGNKTLTDELHMLDHLDLREVYKFIQFRCQDLFHTCRWRGNPVNCCEVI 228
            |.......:.|...:..|     :.|..|:||:..|:...:.:||.::...|.|:....:||::.
  Fly   152 AYDGFSFHKFNAFDSLLG-----ESLDELNHLNFTEIVIQMSWRCDEILRDCHWQTASRDCCKLF 211

  Fly   229 EYQFTEAGLCFVFNTEISPASRQKAREDKYYPLRTPHYGEGSGLDLFLRLNRSFIRPGKRGIN-- 291
            ..:....|.|..||    ...:::..|.          |..:||.|.|.|......||..|:.
  Fly   212 RPRRLPLGYCLAFN----ELEKRRGTET----------GINTGLLLRLLLREGQHAPGNSGLKGF 262

  Fly   292 -VMIKQPQQWSDV-VRHVPHEAHTRISITPRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPD 354
             :.:.:...|... :..||| :.|.:::|..:...||.|.::....|.|:...|.::.|::....
  Fly   263 WLTVVESSVWFGFPIEVVPH-SRTNVAVTAVYHYFDESTLSLPSSWRHCVMDYEEESEHFRTLEG 326

  Fly   355 FEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDKDNFTACKASDFKCLYDNRFTFSIERHPEEDD 419
            .:|.:.||::.|.|.::|..|.|:..:|:|.|   |:.||:..|..||..:.........|.|..
  Fly   327 QKYMLENCQAECQQRYLLRYCNCTVDLFYPPS---NYPACRLKDLPCLAAHNHLLQNFEQPGEHP 388

  Fly   420 FVKNPFKESMICDCFTSCSQLVFDRVFTTTT----------LDNNETDTEAGTMRLDIFYQSGWF 474
            :|... :..::|:|..:|..|      |..|          |..|.:..|  :|.|:::::....
  Fly   389 YVHRE-ESGLVCECLHNCKSL------TLLTDMRKSVQQPWLQPNSSAIE--SMWLNVYFKKPSM 444

  Fly   475 IQYQTNMRFTFVELLASFGGIIGLFLGASLLSAFELAYY 513
            :.|:||:.:|:|:|:.|||||..|.||.|::|..|..::
  Fly   445 LVYKTNLIYTWVDLIVSFGGICQLCLGCSIISLIEFVFF 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	123/476 (26%)
ppk14	NP_609017.2	ASC	45..483	CDD:279230	123/476 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4697
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I3586
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28677
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	1	1.000	-	-		FOG0009975
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.080